ELAC1 - elaC ribonuclease Z 1 Gene

Homo sapiens

Also known as D29

Gene ID: 55520 | Gene type: protein coding

About ELAC1

Cytogenetic location: 18q21.2 Genomic coordinates (GRCh38): 18:50,968,040-50,988,121 (from NCBI)

This gene has 4 transcripts (splice variants), 187 orthologues and 1 paralogue. Ubiquitous expression in thyroid (RPKM 4.4), testis (RPKM 3.5) and 25 other tissues.

Summary

Predicted to enable 3'-tRNA processing endoribonuclease activity. Predicted to be involved in tRNA 3'-trailer cleavage, endonucleolytic. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ELAC1 Products(1)

mRNA	Protein	Name
NM_018696.3	NP_061166.1	zinc phosphodiesterase ELAC protein 1

ELAC1 Protein Structure

Lactamase_B_2

0
100
200
300
363 a.a.

Protein Preferred Names

Protein Names

zinc phosphodiesterase ELAC protein 1

RNase Z 1

Related Diseases

Diseases

Alias

Hairy Tongue

Overgrowth Of Filiform Papillae

Tongue, Hairy

Urethral Diverticulum

Urethral Sacculation

Mitochondrial Dna Depletion Syndrome 4b

Mitochondrial Neurogastrointestinal Encephalopathy Syndrome	Mngie Syndrome
Thymidine Phosphorylase Deficiency	MTDPS4B
Mitochondrial Neurogastrointestinal Encephalopathy Disease	Mngie
Myoneurogastrointestinal Encephalopathy Syndrome	Ogimd
Oculogastrointestinal Muscular Dystrophy	Polip
Polyneuropathy, Ophthalmoplegia, Leukoencephalopathy, And Intestinal Pseudo-Obstruction	Mitochondrial Neurogastrointestinal Encephalopathy Syndrome, Polg-Related
Mngie, Polg-Related	Mepop
Mitochondrial Myopathy With Sensorimotor Polyneuropathy, Ophthalmoplegia, And Pseudo-Obstruction	Mngie Disease
Mitochondrial Dna Depletion Syndrome 4b Mngie Type	Mitochondrial Neurogastrointestinal Encephalopathy Syndrome Polg-Related
Mngie Polg-Related	Mitochondrial Dna Depletion Syndrome, Type 4b
Visceral Myopathy Familial External Ophthalmoplegia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04290	ELAC1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	ELAC1	VGNC	VGNC:107703
Canis familiaris	ELAC1	VGNC	VGNC:56917
Macaca mulatta	ELAC1	VGNC	VGNC:97764
Rattus norvegicus	ELAC1	RGD	RGD:1304757
Bos taurus	ELAC1	VGNC	VGNC:97267
Mus musculus	ELAC1	MGD	MGI:1890495

Name
Email *

	Sorry, but the email address you supplied was invalid.