INTS8 - integrator complex subunit 8 Gene

Also Known as INT8; NEDCHS; C8orf52

Species: Homo sapiens (human)

Gene Type: protein coding
Gene ID: 55656

Summary

This gene encodes a subunit of the Integrator complex which is involved in the cleavage of small nuclear RNAs U1 and U2 within the nucleus. The encoded protein associates with RNA polymerase II and is recruited to the U1 and U2 small nuclear RNA genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]

INTS8 Products (1)

mRNA Protein Name
XM_047421952.1 XP_047277908.1 integrator complex subunit 8 isoform X2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16239144 GOA
Biological Process GO Annotation Evidence References Source
involved in snRNA processing IDA
IDA: Inferred from direct assay
16239144 GOA
Cellular Component GO Annotation Evidence References Source
part of integrator complex IDA
IDA: Inferred from direct assay
16239144 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

integrator complex subunit 8

  • protein kaonashi-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-34505 1-Methyl-5-pyrazolecarboxylic acid 99.83% Unkown
HY-183088 Cl-C6-PEG8-NH2 hydrochloride / Unkown