C1orf112 - chromosome 1 open reading frame 112 Gene

Also Known as Apolo1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55732

About C1orf112

This gene has 9 transcripts (splice variants) and 208 orthologues. Ubiquitous expression in testis (RPKM 5.7), lymph node (RPKM 3.2) and 24 other tissues.

C1orf112 Products (11)

mRNA Protein Name
NM_001320047.2 NP_001306976.1 uncharacterized protein C1orf112 isoform 1
NM_001320048.2 NP_001306977.1 uncharacterized protein C1orf112 isoform 2
NM_001320050.2 NP_001306979.1 uncharacterized protein C1orf112 isoform 3
NM_001320051.2 NP_001306980.1 uncharacterized protein C1orf112 isoform 4
NM_001363739.2 NP_001350668.1 uncharacterized protein C1orf112 isoform 5
NM_001366768.1 NP_001353697.1 uncharacterized protein C1orf112 isoform 6
NM_001366769.1 NP_001353698.1 uncharacterized protein C1orf112 isoform 7
NM_001366770.1 NP_001353699.1 uncharacterized protein C1orf112 isoform 8
NM_001366771.1 NP_001353700.1 uncharacterized protein C1orf112 isoform 5
NM_001366772.1 NP_001353701.1 uncharacterized protein C1orf112 isoform 5
NM_001366773.1 NP_001353702.1 uncharacterized protein C1orf112 isoform 5

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables protein kinase binding IDA
IDA: Inferred from direct assay
34260926 GOA
Biological Process GO Annotation Evidence References Source
involved in chromosome segregation IMP
IMP: Inferred from mutant phenotype
34260926 GOA
involved in interstrand cross-link repair IMP
IMP: Inferred from mutant phenotype
37256941 GOA
involved in mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
34260926 GOA
involved in regulation of protein kinase activity IMP
IMP: Inferred from mutant phenotype
34260926 GOA
Cellular Component GO Annotation Evidence References Source
located in chromosome, centromeric region IDA
IDA: Inferred from direct assay
34260926 GOA
located in kinetochore IDA
IDA: Inferred from direct assay
34260926 GOA
located in midbody IDA
IDA: Inferred from direct assay
34260926 GOA
located in nucleus IDA
IDA: Inferred from direct assay
34260926 GOA
located in spindle midzone IDA
IDA: Inferred from direct assay
34260926 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

C1orf112 Protein Structure

DUF4487

DUF4487: Domain of unknown function (DUF4487) (176 - 728)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 853 a.a.
Protein Preferred Names Protein Names

uncharacterized protein C1orf112

  • associating protein with POLO1

Related Diseases

Diseases Alias
Adiaspiromycosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01710 C1orf112 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus C1orf112 VGNC VGNC:52639
Canis familiaris C1orf112 VGNC VGNC:52585
Macaca mulatta C1orf112 VGNC VGNC:70385
Mus musculus C1orf112 MGD MGI:3590554
Rattus norvegicus C1orf112 RGD RGD:1563470
Felis catus C1orf112 VGNC VGNC:60802
Others C1orf112 NCBI