2. Gene
  3. CENPN - centromere protein N Gene

CENPN - centromere protein N Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as BM039; CENP-N; ICEN32; C16orf60

Gene ID: 55839 | Gene type: protein coding

About CENPN

Cytogenetic location: 16q23.2 Genomic coordinates (GRCh38): 16:81,007,214-81,033,107 (from NCBI)

This gene has 9 transcripts (splice variants) and 212 orthologues. Ubiquitous expression in prostate (RPKM 4.4), bone marrow (RPKM 3.9) and 25 other tissues.

Summary

The protein encoded by this gene forms part of the nucleosome-associated complex and is important for kinetochore assembly. It is bound to kinetochores during S phase and G2 and recruits other proteins to the centromere. Pseudogenes of this gene are located on chromosome 2. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]

CENPN Products(5)

mRNA Protein Name
NM_001100624.3 NP_001094094.2 centromere protein N isoform 2
NM_001100625.3 NP_001094095.2 centromere protein N isoform 1
NM_001270473.2 NP_001257402.1 centromere protein N isoform 4
NM_001270474.2 NP_001257403.1 centromere protein N isoform 5
NM_018455.6 NP_060925.2 centromere protein N isoform 3

CENPN Protein Structure

CENP-N

CENP-N: Kinetochore protein CHL4 like (5 - 339)

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  • 300
  • 339 a.a.
Protein Preferred Names Protein Names

centromere protein N

interphase centromere complex protein 32

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02486 CENPN Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta CENPN VGNC VGNC:71146
Mus musculus CENPN MGD MGI:1919405
Bos taurus CENPN VGNC VGNC:27182
Canis familiaris CENPN VGNC VGNC:39109
Rattus norvegicus CENPN RGD RGD:1310953