CENPN - centromere protein N Gene

Also Known as BM039; CENP-N; ICEN32; C16orf60

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55839

About CENPN

Cytogenetic location: 16q23.2 Genomic coordinates (GRCh38): 16:81,007,214-81,033,107 (from NCBI)

This gene has 9 transcripts (splice variants) and 212 orthologues. Ubiquitous expression in prostate (RPKM 4.4), bone marrow (RPKM 3.9) and 25 other tissues.

Summary

The protein encoded by this gene forms part of the nucleosome-associated complex and is important for kinetochore assembly. It is bound to kinetochores during S phase and G2 and recruits Other proteins to the centromere. Pseudogenes of this gene are located on chromosome 2. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]

CENPN Products (5)

mRNA Protein Name
NM_001100624.3 NP_001094094.2 centromere protein N isoform 2
NM_001100625.3 NP_001094095.2 centromere protein N isoform 1
NM_001270473.2 NP_001257402.1 centromere protein N isoform 4
NM_001270474.2 NP_001257403.1 centromere protein N isoform 5
NM_018455.6 NP_060925.2 centromere protein N isoform 3

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Cellular Component GO Annotation Evidence References Source
part of inner kinetochore IPI
IPI: Inferred from physical interaction
36085283 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CENPN Protein Structure

CENP-N

CENP-N: Kinetochore protein CHL4 like (5 - 339)

  • 0
  • 100
  • 200
  • 300
  • 339 a.a.
Protein Preferred Names Protein Names

centromere protein N

  • interphase centromere complex protein 32

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02486 CENPN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21521 Cenpn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28039 Cenpn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta CENPN VGNC VGNC:71146
Mus musculus CENPN MGD MGI:1919405
Bos taurus CENPN VGNC VGNC:27182
Canis familiaris CENPN VGNC VGNC:39109
Rattus norvegicus CENPN RGD RGD:1310953
Others CENPN NCBI