GPRC5C - G protein-coupled receptor class C group 5 member C Gene

Also Known as RAIG3; RAIG-3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55890

About GPRC5C

Cytogenetic location: 17q25.1 Genomic coordinates (GRCh38): 17:74,432,088-74,451,658 (from NCBI)

This gene has 13 transcripts (splice variants), 265 orthologues and 3 paralogues. Broad expression in kidney (RPKM 15.6), thyroid (RPKM 14.0) and 21 other tissues.

Summary

The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

GPRC5C Products (4)

mRNA Protein Name
NM_001366261.2 NP_001353190.1 G-protein coupled receptor family C group 5 member C isoform c precursor
NM_001366262.2 NP_001353191.1 G-protein coupled receptor family C group 5 member C isoform a precursor
NM_018653.5 NP_061123.4 G-protein coupled receptor family C group 5 member C isoform a precursor
NM_022036.4 NP_071319.3 G-protein coupled receptor family C group 5 member C isoform a precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
part of receptor complex IDA
IDA: Inferred from direct assay
23382219 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GPRC5C Protein Structure

7tm_3

7tm_3: 7 transmembrane sweet-taste receptor of 3 GCPR (105 - 346)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 486 a.a.
Protein Preferred Names Protein Names

G-protein coupled receptor family C group 5 member C

  • orphan G-protein coupled receptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05751 GPRC5C Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus GPRC5C MGD MGI:1917605
Rattus norvegicus GPRC5C RGD RGD:1311408
Macaca mulatta GPRC5C VGNC VGNC:99155
Felis catus GPRC5C VGNC VGNC:99073
Canis familiaris GPRC5C VGNC VGNC:55639
Others GPRC5C NCBI