GPRC5C - G protein-coupled receptor class C group 5 member C Gene

Homo sapiens

Also known as RAIG3; RAIG-3

Gene ID: 55890 | Gene type: protein coding

About GPRC5C

Cytogenetic location: 17q25.1 Genomic coordinates (GRCh38): 17:74,432,088-74,451,658 (from NCBI)

This gene has 13 transcripts (splice variants), 265 orthologues and 3 paralogues. Broad expression in kidney (RPKM 15.6), thyroid (RPKM 14.0) and 21 other tissues.

Summary

The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

GPRC5C Products(4)

mRNA	Protein	Name
NM_001366261.2	NP_001353190.1	G-protein coupled receptor family C group 5 member C isoform c precursor
NM_001366262.2	NP_001353191.1	G-protein coupled receptor family C group 5 member C isoform a precursor
NM_018653.5	NP_061123.4	G-protein coupled receptor family C group 5 member C isoform a precursor
NM_022036.4	NP_071319.3	G-protein coupled receptor family C group 5 member C isoform a precursor

GPRC5C Protein Structure

7tm_3

0
100
200
300
400
486 a.a.

Protein Preferred Names

Protein Names

G-protein coupled receptor family C group 5 member C

orphan G-protein coupled receptor

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05751	GPRC5C Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	GPRC5C	MGD	MGI:1917605
Rattus norvegicus	GPRC5C	RGD	RGD:1311408
Macaca mulatta	GPRC5C	VGNC	VGNC:99155
Felis catus	GPRC5C	VGNC	VGNC:99073
Canis familiaris	GPRC5C	VGNC	VGNC:55639

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