INKA2 - inka box actin regulator 2 Gene
Also Known as FAM212B; C1orf183
Species: Homo sapiens
About INKA2
This gene has 5 transcripts (splice variants), 199 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 6.5), heart (RPKM 3.4) and 23 other tissues.
Summary
Enables protein kinase binding activity. Predicted to be involved in negative regulation of catalytic activity. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
INKA2 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_019099.5 | NP_061972.1 | PAK4-inhibitor INKA2 isoform 1 |
| NM_198926.2 | NP_945120.1 | PAK4-inhibitor INKA2 isoform 2 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein kinase binding |
IPI
IPI: Inferred from physical interaction
|
26607847 | GOA |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
26607847 | GOA |
INKA2 Protein Structure
FAM212: FAM212 family (118 - 176)
- 0
- 100
- 200
- 297 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
PAK4-inhibitor INKA2 |
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Macaca mulatta | INKA2 | VGNC | VGNC:106388 |
| Bos taurus | INKA2 | VGNC | VGNC:50127 |
| Mus musculus | INKA2 | MGD | MGI:1923497 |
| Rattus norvegicus | INKA2 | RGD | RGD:1306526 |
| Others | INKA2 | NCBI |