RAB5IF - RAB5 interacting factor Gene

Also Known as OPTI; RIP5; RCAF1; CFSMR2; PNAS-11; C20orf24

Species: Homo sapiens (human)

Gene Type: protein coding
Gene ID: 55969

Summary

Involved in mitochondrial respirasome assembly. Located in mitochondrial respirasome. [provided by Alliance of Genome Resources, Apr 2022]

RAB5IF Products (1)

mRNA Protein Name
NM_018840.5 NP_061328.1 GEL complex subunit OPTI isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
31536960 GOA
Biological Process GO Annotation Evidence References Source
involved in mitochondrial respirasome assembly IMP
IMP: Inferred from mutant phenotype
31536960 GOA
involved in multi-pass transmembrane protein insertion into ER membrane IDA
IDA: Inferred from direct assay
36261522 GOA
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IMP
IMP: Inferred from mutant phenotype
31536960 GOA
part of multi-pass translocon complex IDA
IDA: Inferred from direct assay
36261522 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

GEL complex subunit OPTI

  • obligate partner of TMCO1 insertase

  • rab5-interacting protein

  • respirasome complex assembly factor 1

  • uncharacterized protein C20orf24

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11589 RABIF Human Pre-designed siRNA Set A Pre-designed Set / Unkown