2. Gene
  3. Pigb - phosphatidylinositol glycan anchor biosynthesis, class B Gene

Pigb - phosphatidylinositol glycan anchor biosynthesis, class B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Pig-b

Gene ID: 55981 | Gene type: protein coding

About Pigb

Summary

Predicted to enable alpha-1,2-mannosyltransferase activity. Predicted to be involved in GPI anchor biosynthetic process and mannosylation. Predicted to act upstream of or within GPI anchor metabolic process. Located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 80. Orthologous to human PIGB (phosphatidylinositol glycan anchor biosynthesis class B). [provided by Alliance of Genome Resources, Apr 2022]

Pigb Products(2)

mRNA Protein Name
NM_001410648.1 NP_001397577.1 GPI mannosyltransferase 3
NM_018889.4 NP_061377.2 GPI mannosyltransferase 3
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
8861954 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

GPI mannosyltransferase 3

GPI mannosyltransferase III

GPI-MT-III

involved in GPI-anchor biosynthesis

phosphatidylinositol glycan, class B

phosphatidylinositol-glycan biosynthesis class B protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10488 PIGB Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pigb NCBI NCBI:9488