Pdzrn3 - PDZ domain containing RING finger 3 Gene

Mus musculus

Also known as LNX3; Semcap3; SEMACAP3; 1110020C07Rik

Gene ID: 55983 | Gene type: protein coding

About Pdzrn3

Summary

Enables ubiquitin protein Ligase activity. Involved in neuromuscular junction development and protein ubiquitination. Located in neuromuscular junction. Is expressed in forebrain; genitourinary system; and tail paraxial mesenchyme. Orthologous to human PDZRN3 (PDZ domain containing ring finger 3). [provided by Alliance of Genome Resources, Apr 2022]

Pdzrn3 Products(1)

mRNA	Protein	Name
NM_018884.2	NP_061372.2	E3 ubiquitin-protein ligase PDZRN3

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	17576800	MGI
enables ubiquitin protein ligase activity	IDA IDA: Inferred from direct assay	17576800	MGI
enables ubiquitin-protein transferase activity	IDA IDA: Inferred from direct assay	17576800	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in neuromuscular junction development	IMP IMP: Inferred from mutant phenotype	17576800	MGI
involved in protein ubiquitination	IDA IDA: Inferred from direct assay	17576800	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in neuromuscular junction	IDA IDA: Inferred from direct assay	17576800	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

E3 ubiquitin-protein ligase PDZRN3

PDZ domain containing RING finger 3A	PDZ domain-containing RING finger protein 3
RING-type E3 ubiquitin transferase PDZRN3	semaphorin cytoplasmic domain-associated protein 3
semaphorin cytoplasmic domain-associated protein 3A

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10307	PDZRN3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pdzrn3	NCBI	NCBI:23024

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