Dgke - diacylglycerol kinase, epsilon Gene

Also Known as DGK; DAGK6; DGK-epsilon

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56077

Summary

Predicted to enable diacylglycerol kinase activity. Involved in modulation of chemical synaptic transmission and phosphatidylinositol biosynthetic process. Located in glutamatergic synapse. Human ortholog(s) of this gene implicated in nephrotic syndrome type 7. Orthologous to human DGKE (diacylglycerol kinase epsilon). [provided by Alliance of Genome Resources, Apr 2022]

Dgke Products (2)

mRNA Protein Name
NM_001362845.1 NP_001349774.1 diacylglycerol kinase epsilon isoform 2
NM_019505.4 NP_062378.1 diacylglycerol kinase epsilon isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
11287665 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
11287665 MGI
involved in phosphatidylinositol biosynthetic process IMP
IMP: Inferred from mutant phenotype
19744926 MGI
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
11287665 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
11287665 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

diacylglycerol kinase epsilon

  • DAG kinase epsilon

  • diglyceride kinase epsilon

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03718 DGKE Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dgke NCBI NCBI:8526