Dgke - diacylglycerol kinase, epsilon Gene

Mus musculus

Also known as DGK; DAGK6; DGK-epsilon

Gene ID: 56077 | Gene type: protein coding

About Dgke

Summary

Predicted to enable diacylglycerol kinase activity. Involved in modulation of chemical synaptic transmission and phosphatidylinositol biosynthetic process. Located in glutamatergic synapse. Human ortholog(s) of this gene implicated in nephrotic syndrome type 7. Orthologous to human DGKE (diacylglycerol kinase epsilon). [provided by Alliance of Genome Resources, Apr 2022]

Dgke Products(2)

mRNA	Protein	Name
NM_001362845.1	NP_001349774.1	diacylglycerol kinase epsilon isoform 2
NM_019505.4	NP_062378.1	diacylglycerol kinase epsilon isoform 1

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	Reference	Source
involved in modulation of chemical synaptic transmission	IDA IDA: Inferred from direct assay	11287665	MGI
involved in modulation of chemical synaptic transmission	IMP IMP: Inferred from mutant phenotype	11287665	MGI
involved in phosphatidylinositol biosynthetic process	IMP IMP: Inferred from mutant phenotype	19744926	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	11287665	MGI
is active in glutamatergic synapse	IMP IMP: Inferred from mutant phenotype	11287665	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

diacylglycerol kinase epsilon

DAG kinase epsilon

diglyceride kinase epsilon

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03718	DGKE Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Dgke	NCBI	NCBI:8526

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