Astn2 - astrotactin 2 Gene

Also Known as 1d8; Astnl; bM452J22.1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56079

Summary

Predicted to enable calcium ion binding activity and inositol 1,3,4,5 tetrakisphosphate binding activity. Acts upstream of or within establishment of body hair planar orientation and negative regulation of protein localization to cell surface. Located in cell pole and endosome. Is integral component of membrane. Is expressed in several structures, including central nervous system; embryo mesenchyme; respiratory system; sensory organ; and skin. Orthologous to human ASTN2 (astrotactin 2). [provided by Alliance of Genome Resources, Apr 2022]

Astn2 Products (2)

mRNA Protein Name
NM_019514.3 NP_062387.2 astrotactin-2 isoform a precursor
NM_207109.2 NP_996992.1 astrotactin-2 isoform b precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
20573900 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within establishment of body hair planar orientation IGI
IGI: Inferred from genetic interaction
26418459 MGI
acts upstream of or within negative regulation of protein localization to cell surface IDA
IDA: Inferred from direct assay
20573900 MGI
acts upstream of protein localization to cell surface IDA
IDA: Inferred from direct assay
20573900 MGI
Cellular Component GO Annotation Evidence References Source
located in cell pole IDA
IDA: Inferred from direct assay
20573900 MGI
located in endosome IDA
IDA: Inferred from direct assay
20573900 MGI
located in membrane IDA
IDA: Inferred from direct assay
20573900 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

astrotactin-2

  • bM243L4.1 (astrotactin 2)

  • bM264P11.1 (astrotactin 2)

  • bM383P24.1 (astrotactin 2)

  • bM423P8.1 (astrotactin 2)

  • bM468K2.1 (astrotactin 2)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01113 ASTN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Astn2 NCBI NCBI:23245