2. Gene
  3. Tdp2 - tyrosyl-DNA phosphodiesterase 2 Gene

Tdp2 - tyrosyl-DNA phosphodiesterase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ttrap; D13Ertd656e

Gene ID: 56196 | Gene type: protein coding

About Tdp2

Summary

Predicted to enable several functions, including metal ion binding activity; phosphoric diester hydrolase activity; and single-stranded DNA binding activity. Predicted to be involved in double-strand break repair and neuron development. Predicted to act upstream of or within DNA repair. Predicted to be located in aggresome and nuclear body. Predicted to be active in PML body and cytoplasm. Is expressed in several structures, including alimentary system; limb; liver; spleen; and testis. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 23. Orthologous to human TDP2 (tyrosyl-DNA phosphodiesterase 2). [provided by Alliance of Genome Resources, Apr 2022]

Tdp2 Products(1)

mRNA Protein Name
NM_019551.2 NP_062424.1 tyrosyl-DNA phosphodiesterase 2
Protein Preferred Names Protein Names

tyrosyl-DNA phosphodiesterase 2

5'-Tyr-DNA phosphodiesterase

5'-tyrosyl-DNA phosphodiesterase

TRAF and TNF receptor-associated protein

tyr-DNA phosphodiesterase 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-162753 ZW-1226 Inhibitor 98.13% Unkown
HY-RS14333 TDP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tdp2 NCBI NCBI:51567