Patz1 - POZ (BTB) and AT hook containing zinc finger 1 Gene

Also Known as Mazr; Patz; Zfp278; 8430401L15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56218

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in negative regulation of endothelial cell migration and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including T cell differentiation; male gonad development; and spermatogenesis. Located in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; limb bud; nervous system; and sensory organ. Orthologous to human PATZ1 (POZ/BTB and AT hook containing zinc finger 1). [provided by Alliance of Genome Resources, Apr 2022]

Patz1 Products (3)

mRNA Protein Name
NM_001253690.1 NP_001240619.1 POZ (BTB) and AT hook-containing zinc finger 1 isoform 2
NM_001253691.1 NP_001240620.1 POZ (BTB) and AT hook-containing zinc finger 1 isoform 3
NM_019574.3 NP_062520.1 POZ (BTB) and AT hook-containing zinc finger 1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
16491076 MGI
enables chromatin binding IDA
IDA: Inferred from direct assay
16491076 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16491076 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within T cell differentiation IDA
IDA: Inferred from direct assay
16491076 MGI
acts upstream of or within male gonad development IMP
IMP: Inferred from mutant phenotype
18241078 MGI
involved in negative regulation of endothelial cell migration IMP
IMP: Inferred from mutant phenotype
27983982 MGI
acts upstream of or within positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
10669750 MGI
acts upstream of or within regulation of DNA-templated transcription IPI
IPI: Inferred from physical interaction
16491076 MGI
acts upstream of or within regulation of gene expression IDA
IDA: Inferred from direct assay
16491076 MGI
acts upstream of or within spermatogenesis IMP
IMP: Inferred from mutant phenotype
18241078 MGI
Cellular Component GO Annotation Evidence References Source
located in male germ cell nucleus IDA
IDA: Inferred from direct assay
18241078 MGI
located in nucleus IDA
IDA: Inferred from direct assay
16491076 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

POZ (BTB) and AT hook-containing zinc finger 1

  • BTB/POZ domain zinc finger transcription factor

  • POZ-, AT hook-, and zinc finger-containing protein 1

  • POZ-AT hook-zinc finger protein

  • protein kinase A RI subunit alpha-associated protein

  • transcription factor (MAZ-related) MAZR

  • zinc finger and BTB doma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-175601 DD-04-038 Degrader / Unkown
HY-RS10086 PATZ1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Patz1 NCBI NCBI:23598