WDR45B - WD repeat domain 45B Gene

Also Known as WIPI3; WDR45L; WIPI-3; NEDSBAS

Species: Homo sapiens (human)

Gene Type: protein coding
Gene ID: 56270

Summary

This gene encodes a member of the WIPI or SVP1 family of WD40 repeat-containing proteins. The protein contains seven WD40 repeats that are thought to fold into a beta-propeller structure that mediates protein-protein interactions, and a conserved motif for interaction with Phospholipids. The human genome contains several pseudogenes of this gene. [provided by RefSeq, Jul 2008]

WDR45B Products (1)

mRNA Protein Name
XM_054316692.1 XP_054172667.1 WD repeat domain phosphoinositide-interacting protein 3 isoform X4

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables TSC1-TSC2 complex binding IDA
IDA: Inferred from direct assay
28561066 GOA
enables phosphatidylinositol-3,5-bisphosphate binding IDA
IDA: Inferred from direct assay
28561066 GOA
enables phosphatidylinositol-3-phosphate binding IDA
IDA: Inferred from direct assay
28561066 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
28561066 GOA
Biological Process GO Annotation Evidence References Source
involved in autophagosome assembly IMP
IMP: Inferred from mutant phenotype
28561066 GOA
involved in cellular response to starvation IDA
IDA: Inferred from direct assay
28561066 GOA
Cellular Component GO Annotation Evidence References Source
located in lysosome IDA
IDA: Inferred from direct assay
28561066 GOA
located in phagophore assembly site IDA
IDA: Inferred from direct assay
28561066 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

WD repeat domain phosphoinositide-interacting protein 3

  • WD repeat protein 45-like

  • WD repeat-containing protein 45-like

  • WD repeat-containing protein 45B

  • WDR45-like protein

  • WIPI3 long

  • WIPI49-like protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15781 WDR45 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15789 WDR5B Human Pre-designed siRNA Set A / Unkown