Snx1 - sorting nexin 1 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56440

Summary

Predicted to enable phosphatidylinositol binding activity; protein dimerization activity; and signaling receptor binding activity. Involved in neuron projection development. Acts upstream of or within negative regulation of transforming growth factor beta receptor signaling pathway. Located in several cellular components, including dendritic spine; early endosome; and postsynaptic density. Is active in postsynaptic density, intracellular component. Is extrinsic component of postsynaptic endosome membrane. Is expressed in embryo; epiblast; primitive endoderm; and yolk sac. Orthologous to human SNX1 (sorting nexin 1). [provided by Alliance of Genome Resources, Apr 2022]

Snx1 Products (1)

mRNA Protein Name
NM_019727.2 NP_062701.2 sorting nexin-1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15239668 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of transforming growth factor beta receptor signaling pathway IDA
IDA: Inferred from direct assay
15239668 MGI
involved in neuron projection development IDA
IDA: Inferred from direct assay
24261326 MGI
Cellular Component GO Annotation Evidence References Source
located in dendritic spine IDA
IDA: Inferred from direct assay
24261326 MGI
located in early endosome IDA
IDA: Inferred from direct assay
19549681 MGI
located in endosome IDA
IDA: Inferred from direct assay
15078902 MGI
is active in extrinsic component of postsynaptic endosome membrane IDA
IDA: Inferred from direct assay
24261326 MGI
located in membrane IDA
IDA: Inferred from direct assay
9819414 MGI
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
19549681 MGI
located in postsynaptic density IDA
IDA: Inferred from direct assay
24261326 MGI
is active in postsynaptic density, intracellular component IDA
IDA: Inferred from direct assay
24261326 MGI
located in postsynaptic density, intracellular component IDA
IDA: Inferred from direct assay
24261326 MGI
is active in postsynaptic density, intracellular component IEP
IEP: Inferred from expression pattern
24261326 MGI
located in presynapse IDA
IDA: Inferred from direct assay
24261326 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sorting nexin-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13522 SNX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Snx1 NCBI NCBI:6642