2. Gene
  3. Zbtb20 - zinc finger and BTB domain containing 20 Gene

Zbtb20 - zinc finger and BTB domain containing 20 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as HOF; J20; DPZF; Oda8; ODA-8S; Zfp288; D16Wsu73e; 1300017A20Rik; 7330412A13Rik; A930017C21Rik; Tg(PDGFB-APPSwInd)20Lms

Gene ID: 56490 | Gene type: protein coding

About Zbtb20

Summary

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity. Involved in several processes, including cellular response to glucose stimulus; positive regulation of glycolytic process; and regulation of gene expression. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Orthologous to human ZBTB20 (zinc finger and BTB domain containing 20). [provided by Alliance of Genome Resources, Apr 2022]

Zbtb20 Products(6)

mRNA Protein Name
NM_001285805.1 NP_001272734.1 zinc finger and BTB domain-containing protein 20 isoform L
NM_001393397.1 NP_001380326.1 zinc finger and BTB domain-containing protein 20 isoform L
NM_001393398.1 NP_001380327.1 zinc finger and BTB domain-containing protein 20 isoform L
NM_001393399.1 NP_001380328.1 zinc finger and BTB domain-containing protein 20 isoform S
NM_019778.2 NP_062752.2 zinc finger and BTB domain-containing protein 20 isoform L
NM_181058.1 NP_851401.1 zinc finger and BTB domain-containing protein 20 isoform S
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables DNA binding IDA
IDA: Inferred from direct assay
11744704 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
18669658 MGI
enables transcription cis-regulatory region binding IDA
IDA: Inferred from direct assay
28327662 MGI
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to glucose stimulus IMP
IMP: Inferred from mutant phenotype
28327662 MGI
involved in lipid homeostasis IMP
IMP: Inferred from mutant phenotype
28327662 MGI
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
23776228 MGI
involved in negative regulation of gene expression IMP
IMP: Inferred from mutant phenotype
23776228 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
18669658 MGI
involved in positive regulation of glycolytic process IMP
IMP: Inferred from mutant phenotype
28327662 MGI
involved in positive regulation of interferon-beta production IDA
IDA: Inferred from direct assay
23776228 MGI
involved in positive regulation of interferon-beta production IMP
IMP: Inferred from mutant phenotype
23776228 MGI
involved in positive regulation of interleukin-6 production IDA
IDA: Inferred from direct assay
23776228 MGI
involved in positive regulation of interleukin-6 production IMP
IMP: Inferred from mutant phenotype
23776228 MGI
involved in positive regulation of lipid biosynthetic process IMP
IMP: Inferred from mutant phenotype
28327662 MGI
involved in positive regulation of tumor necrosis factor production IDA
IDA: Inferred from direct assay
23776228 MGI
involved in positive regulation of tumor necrosis factor production IMP
IMP: Inferred from mutant phenotype
23776228 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
28327662 MGI
located in nucleus IDA
IDA: Inferred from direct assay
11744704 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

zinc finger and BTB domain-containing protein 20

APP Tg

BTB/POZ domain zinc finger factor HOF

PDGF-APPSwInd

PDGF-hAPP695,751,770V171F, KM670/671NL

POZ/zinc finger transcription factor ODA-8

zinc finger protein 288

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15968 ZBTB20 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Zbtb20 NCBI NCBI:26137