Pmfbp1 - polyamine modulated factor 1 binding protein 1 Gene

Also Known as F77; Stap; 1700016D22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56523

Summary

Involved in spermatogenesis. Located in cytoplasm and sperm connecting piece. Is expressed in central nervous system; dorsal root ganglion; and neural retina. Used to study male infertility and spermatogenic failure 31. Human ortholog(s) of this gene implicated in spermatogenic failure 31. Orthologous to human PMFBP1 (polyamine modulated factor 1 binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Pmfbp1 Products (1)

mRNA Protein Name
NM_019938.3 NP_064322.1 polyamine-modulated factor 1-binding protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
34389728 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within gene expression IMP
IMP: Inferred from mutant phenotype
30298696 MGI
acts upstream of or within protein localization IMP
IMP: Inferred from mutant phenotype
34389728 MGI
acts upstream of or within protein-containing complex assembly IMP
IMP: Inferred from mutant phenotype
34389728 MGI
acts upstream of or within regulation of protein localization IMP
IMP: Inferred from mutant phenotype
34389728 MGI
acts upstream of or within spermatid development IMP
IMP: Inferred from mutant phenotype
30298696 MGI
acts upstream of or within spermatogenesis IMP
IMP: Inferred from mutant phenotype
30298696 MGI
involved in spermatogenesis IMP
IMP: Inferred from mutant phenotype
30032984 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
11468771 MGI
is active in sperm flagellum IDA
IDA: Inferred from direct assay
30298696 MGI
is active in sperm head IDA
IDA: Inferred from direct assay
30298696 MGI
is active in sperm head-tail coupling apparatus IDA
IDA: Inferred from direct assay
30298696 MGI
located in sperm head-tail coupling apparatus IDA
IDA: Inferred from direct assay
30032984 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

polyamine-modulated factor 1-binding protein 1

  • PMF-1-binding protein

  • sperm tail-associated protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10763 PMFBP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pmfbp1 NCBI NCBI:83449