Pmfbp1 - polyamine modulated factor 1 binding protein 1 Gene

Mus musculus

Also known as F77; Stap; 1700016D22Rik

Gene ID: 56523 | Gene type: protein coding

About Pmfbp1

Summary

Involved in spermatogenesis. Located in cytoplasm and sperm connecting piece. Is expressed in central nervous system; dorsal root ganglion; and neural retina. Used to study male infertility and spermatogenic failure 31. Human ortholog(s) of this gene implicated in spermatogenic failure 31. Orthologous to human PMFBP1 (polyamine modulated factor 1 binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Pmfbp1 Products(1)

mRNA	Protein	Name
NM_019938.3	NP_064322.1	polyamine-modulated factor 1-binding protein 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	34389728	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within gene expression	IMP IMP: Inferred from mutant phenotype	30298696	MGI
acts upstream of or within protein localization	IMP IMP: Inferred from mutant phenotype	34389728	MGI
acts upstream of or within protein-containing complex assembly	IMP IMP: Inferred from mutant phenotype	34389728	MGI
acts upstream of or within regulation of protein localization	IMP IMP: Inferred from mutant phenotype	34389728	MGI
acts upstream of or within spermatid development	IMP IMP: Inferred from mutant phenotype	30298696	MGI
acts upstream of or within spermatogenesis	IMP IMP: Inferred from mutant phenotype	30298696	MGI
involved in spermatogenesis	IMP IMP: Inferred from mutant phenotype	30032984	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	11468771	MGI
is active in sperm flagellum	IDA IDA: Inferred from direct assay	30298696	MGI
is active in sperm head	IDA IDA: Inferred from direct assay	30298696	MGI
is active in sperm head-tail coupling apparatus	IDA IDA: Inferred from direct assay	30298696	MGI
located in sperm head-tail coupling apparatus	IDA IDA: Inferred from direct assay	30032984	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

polyamine-modulated factor 1-binding protein 1

PMF-1-binding protein

sperm tail-associated protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10763	PMFBP1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pmfbp1	NCBI	NCBI:83449

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