Mocs1 - molybdenum cofactor synthesis 1 Gene

Also Known as 3110045D15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56738

Summary

Enables GTP 3',8'-cyclase activity and cyclic pyranopterin monophosphate synthase activity. Acts upstream of or within molybdopterin cofactor biosynthetic process. Predicted to be located in cytosol. Predicted to be part of molybdopterin synthase complex. Human ortholog(s) of this gene implicated in molybdenum cofactor deficiency type A. Orthologous to human MOCS1 (molybdenum cofactor synthesis 1). [provided by Alliance of Genome Resources, Apr 2022]

Mocs1 Products (2)

mRNA Protein Name
NM_020042.3 NP_064426.2 molybdenum cofactor biosynthesis protein 1 isoform 1
NM_028464.2 NP_082740.1 molybdenum cofactor biosynthesis protein 1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables GTP 3',8'-cyclase activity IMP
IMP: Inferred from mutant phenotype
17236133 MGI
enables S-adenosyl-L-methionine binding IMP
IMP: Inferred from mutant phenotype
17236133 MGI
enables cyclic pyranopterin monophosphate synthase activity IMP
IMP: Inferred from mutant phenotype
17236133 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within molybdopterin cofactor biosynthetic process IMP
IMP: Inferred from mutant phenotype
12471057 MGI
involved in molybdopterin cofactor biosynthetic process IMP
IMP: Inferred from mutant phenotype
17236133 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

molybdenum cofactor biosynthesis protein 1

  • molybdenum cofactor synthesis-step 1 proteins A and B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08580 MOCS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mocs1 NCBI NCBI:4337