2. Gene
  3. Nfu1 - NFU1 iron-sulfur cluster scaffold Gene

Nfu1 - NFU1 iron-sulfur cluster scaffold Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as CGI-33; Hirip5; 0610006G17Rik

Gene ID: 56748 | Gene type: protein coding

About Nfu1

Summary

Predicted to enable 4 iron, 4 sulfur cluster binding activity and iron ion binding activity. Predicted to be involved in iron-sulfur cluster assembly and protein maturation by iron-sulfur cluster transfer. Located in mitochondrion. Is expressed in several structures, including brain; early embryo; genitourinary system; liver; and spleen. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome 1. Orthologous to human NFU1 (NFU1 iron-sulfur cluster scaffold). [provided by Alliance of Genome Resources, Apr 2022]

Nfu1 Products(2)

mRNA Protein Name
NM_001170591.1 NP_001164062.1 NFU1 iron-sulfur cluster scaffold homolog, mitochondrial isoform 1 precursor
NM_020045.3 NP_064429.2 NFU1 iron-sulfur cluster scaffold homolog, mitochondrial isoform 2 precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
11342215 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NFU1 iron-sulfur cluster scaffold homolog, mitochondrial

HIRA-interacting protein 5

histone cell cycle regulation defective interacting protein 5

mHIRIP5

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09268 NFU1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nfu1 NCBI NCBI:27247