Nfu1 - NFU1 iron-sulfur cluster scaffold Gene

Also Known as CGI-33; Hirip5; 0610006G17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56748

Summary

Predicted to enable 4 iron, 4 sulfur cluster binding activity and iron ion binding activity. Predicted to be involved in iron-sulfur cluster assembly and protein maturation by iron-sulfur cluster transfer. Located in mitochondrion. Is expressed in several structures, including brain; early embryo; genitourinary system; liver; and spleen. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome 1. Orthologous to human NFU1 (NFU1 iron-sulfur cluster scaffold). [provided by Alliance of Genome Resources, Apr 2022]

Nfu1 Products (2)

mRNA Protein Name
NM_001170591.1 NP_001164062.1 NFU1 iron-sulfur cluster scaffold homolog, mitochondrial isoform 1 precursor
NM_020045.3 NP_064429.2 NFU1 iron-sulfur cluster scaffold homolog, mitochondrial isoform 2 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11342215 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NFU1 iron-sulfur cluster scaffold homolog, mitochondrial

  • HIRA-interacting protein 5

  • histone cell cycle regulation defective interacting protein 5

  • mHIRIP5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09268 NFU1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nfu1 NCBI NCBI:27247