Ralgapa1 - Ral GTPase activating protein, alpha subunit 1 Gene

Also Known as GRIPE; Garnl1; Tulip1; mKIAA0884; 2310003F20Rik; 4930400K19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56784

Summary

Predicted to enable GTPase activator activity and protein heterodimerization activity. Acts upstream of or within regulation of transcription, DNA-templated. Located in cytoplasm and nucleus. Is expressed in several structures, including 1st branchial arch; brain; and trunk. Orthologous to human RALGAPA1 (Ral GTPase activating protein catalytic subunit alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

Ralgapa1 Products (5)

mRNA Protein Name
NM_001003719.2 NP_001003719.1 ral GTPase-activating protein subunit alpha-1 isoform 3
NM_001112714.2 NP_001106185.1 ral GTPase-activating protein subunit alpha-1 isoform 2
NM_001286263.1 NP_001273192.1 ral GTPase-activating protein subunit alpha-1 isoform 4
NM_001368814.1 NP_001355743.1 ral GTPase-activating protein subunit alpha-1 isoform 1
NM_019994.5 NP_064378.4 ral GTPase-activating protein subunit alpha-1 isoform 2
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12200424 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of negative effect negative regulation of DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
12200424 MGI
acts upstream of negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
12200424 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
12200424 MGI
located in nucleus IDA
IDA: Inferred from direct assay
12200424 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ral GTPase-activating protein subunit alpha-1

  • GAP-related interacting partner to E12

  • GTPase activating RANGAP domain-like 1

  • GTPase-activating RapGAP domain-like 1

  • p240

  • ral GTPase-activating protein alpha subunit 1

  • tuberin-like protein 1

  • tulip 1 protein

Orthologs Information

Species Symbol Source ID
Homo sapiens Ralgapa1 NCBI NCBI:253959