PSG11 - pregnancy specific beta-1-glycoprotein 11 Gene

Also Known as PSG13; PSG14; PSBG-11; PSBG-13

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 5680

About PSG11

Cytogenetic location: 19q13.31 Genomic coordinates (GRCh38): 19:43,007,656-43,026,469 (from NCBI)

This gene has 13 transcripts (splice variants), 628 orthologues and 24 paralogues. Restricted expression toward placenta (RPKM 77.7).

Summary

The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy. PSGs comprise a subgroup of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily. For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009]

PSG11 Products (3)

mRNA Protein Name
NM_001113410.2 NP_001106881.1 pregnancy-specific beta-1-glycoprotein 11 isoform 2
NM_002785.3 NP_002776.3 pregnancy-specific beta-1-glycoprotein 11 isoform 1 precursor
NM_203287.2 NP_976032.2 pregnancy-specific beta-1-glycoprotein 11 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PSG11 Protein Structure

V-set

V-set: Immunoglobulin V-set domain (40 - 127)

Ig_2

Ig_2: Immunoglobulin domain (148 - 234)

Ig_2

Ig_2: Immunoglobulin domain (245 - 320)

  • 0
  • 100
  • 200
  • 300
  • 335 a.a.
Protein Preferred Names Protein Names

pregnancy-specific beta-1-glycoprotein 11

  • PS-beta-G-11

Related Diseases

Diseases Alias
Mild Pre-Eclampsia

  • Mild Toxemia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11280 PSG11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11288 PSG9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown