Cldn9 - claudin 9 Gene

Also Known as nmf329

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56863

Summary

This intronless gene encodes a member of the Claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is developmentally regulated; it is expressed in neonate kidney, but disappers by adulthood. It is required for the preservation of sensory cells in the hearing organ and the gene deficiency is associated with deafness. [provided by RefSeq, Aug 2010]

Cldn9 Products (1)

mRNA Protein Name
NM_020293.3 NP_064689.2 claudin-9

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within cell-cell junction organization IDA
IDA: Inferred from direct assay
17130295 MGI
acts upstream of or within tight junction organization IDA
IDA: Inferred from direct assay
17130295 MGI
Cellular Component GO Annotation Evidence References Source
located in bicellular tight junction IDA
IDA: Inferred from direct assay
17130295 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
17130295 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

claudin-9

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02777 CLDN9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20380 Cldn9 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26890 Cldn9 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992221 Anti-CLDN9 Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cldn9 NCBI NCBI:9080