Lmbr1 - limb region 1 Gene

Also Known as 1110048D14Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56873

Summary

This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic Hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic Hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. [provided by RefSeq, Jul 2008]

Lmbr1 Products (1)

mRNA Protein Name
NM_020295.3 NP_064691.2 limb region 1 protein
Biological Process GO Annotation Evidence References Source
acts upstream of or within embryonic digit morphogenesis IMP
IMP: Inferred from mutant phenotype
11606546 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

limb region 1 protein

Orthologs Information

Species Symbol Source ID
Homo sapiens Lmbr1 NCBI NCBI:64327