2. Gene
  3. Htr3b - 5-hydroxytryptamine (serotonin) receptor 3B Gene

Htr3b - 5-hydroxytryptamine (serotonin) receptor 3B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 5-HT3B

Gene ID: 57014 | Gene type: protein coding

About Htr3b

Summary

Enables serotonin-gated cation-selective channel activity. Predicted to be involved in several processes, including chemical synaptic transmission; positive regulation of ion transmembrane transporter activity; and regulation of membrane potential. Predicted to act upstream of or within ion transport. Is integral component of plasma membrane. Is expressed in several structures, including adrenal gland; genitourinary system; gut; lung; and nervous system. Human ortholog(s) of this gene implicated in alcohol use disorder and mental depression. Orthologous to human HTR3B (5-hydroxytryptamine receptor 3B). [provided by Alliance of Genome Resources, Apr 2022]

Htr3b Products(1)

mRNA Protein Name
NM_020274.4 NP_064670.1 5-hydroxytryptamine receptor 3B precursor
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables serotonin-gated monoatomic cation channel activity IDA
IDA: Inferred from direct assay
10854267 MGI
Cellular Component GO Annotation Evidence Reference Source
located in plasma membrane IDA
IDA: Inferred from direct assay
10854267 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

5-hydroxytryptamine receptor 3B

5-HT3 receptor subunit B

5-HT3-B

serotonin receptor 3B

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06473 HTR3B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Htr3b NCBI NCBI:9177