Htr3b - 5-hydroxytryptamine (serotonin) receptor 3B Gene

Also Known as 5-HT3B

Species: Mus musculus

Gene Type: protein coding
Gene ID: 57014

Summary

Enables serotonin-gated cation-selective channel activity. Predicted to be involved in several processes, including chemical synaptic transmission; positive regulation of ion transmembrane transporter activity; and regulation of membrane potential. Predicted to act upstream of or within ion transport. Is integral component of plasma membrane. Is expressed in several structures, including adrenal gland; genitourinary system; gut; lung; and nervous system. Human ortholog(s) of this gene implicated in alcohol use disorder and mental depression. Orthologous to human HTR3B (5-hydroxytryptamine receptor 3B). [provided by Alliance of Genome Resources, Apr 2022]

Htr3b Products (1)

mRNA Protein Name
NM_020274.4 NP_064670.1 5-hydroxytryptamine receptor 3B precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables serotonin-gated monoatomic cation channel activity IDA
IDA: Inferred from direct assay
10854267 MGI
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
10854267 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

5-hydroxytryptamine receptor 3B

  • 5-HT3 receptor subunit B

  • 5-HT3-B

  • serotonin receptor 3B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06473 HTR3B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Htr3b NCBI NCBI:9177