2. Gene
  3. Jph3 - junctophilin 3 Gene

Jph3 - junctophilin 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Jp3; JP-3

Gene ID: 57340 | Gene type: protein coding

About Jph3

Summary

Involved in several processes, including exploration behavior; regulation of neuronal synaptic plasticity; and regulation of ryanodine-sensitive calcium-release channel activity. Acts upstream of or within learning; locomotion; and neuromuscular process controlling balance. Located in endoplasmic reticulum membrane and plasma membrane. Part of junctional membrane complex. Is expressed in brain. Human ortholog(s) of this gene implicated in Huntington's disease-like 2. Orthologous to human JPH3 (junctophilin 3). [provided by Alliance of Genome Resources, Apr 2022]

Jph3 Products(1)

mRNA Protein Name
NM_020605.3 NP_065630.1 junctophilin-3
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in exploration behavior IMP
IMP: Inferred from mutant phenotype
16809425 MGI
acts upstream of or within learning IGI
IGI: Inferred from genetic interaction
17347645 MGI
acts upstream of or within locomotion IMP
IMP: Inferred from mutant phenotype
11906164 MGI
involved in memory IMP
IMP: Inferred from mutant phenotype
16809425 MGI
acts upstream of or within neuromuscular process controlling balance IGI
IGI: Inferred from genetic interaction
17347645 MGI
acts upstream of or within regulation of neuronal synaptic plasticity IGI
IGI: Inferred from genetic interaction
17347645 MGI
involved in regulation of neuronal synaptic plasticity IMP
IMP: Inferred from mutant phenotype
16809425 MGI
involved in regulation of ryanodine-sensitive calcium-release channel activity IMP
IMP: Inferred from mutant phenotype
16809425 MGI
Cellular Component GO Annotation Evidence Reference Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
16809425 MGI
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
16809425 MGI
part of junctional membrane complex IDA
IDA: Inferred from direct assay
16809425 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
16809425 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

junctophilin-3

junctophilin type 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07047 JPH3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Jph3 NCBI NCBI:57338