AS3MT - arsenite methyltransferase Gene

Also Known as CYT19

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57412

About AS3MT

Cytogenetic location: 10q24.32 Genomic coordinates (GRCh38): 10:102,869,470-102,901,899 (from NCBI)

This gene has 1 transcript (splice variant), 190 orthologues and 4 paralogues. Biased expression in adrenal (RPKM 88.8), liver (RPKM 11.0) and 5 other tissues.

Summary

AS3MT catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to trivalent arsenical and may play a role in arsenic metabolism (Lin et al., 2002 [PubMed 11790780]).[supplied by OMIM, Mar 2008]

AS3MT Products (1)

mRNA Protein Name
NM_020682.4 NP_065733.2 arsenite methyltransferase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables arsenite methyltransferase activity IDA
IDA: Inferred from direct assay
25997655 GOA
Biological Process GO Annotation Evidence References Source
involved in arsonoacetate metabolic process IDA
IDA: Inferred from direct assay
25997655 GOA
involved in methylation IDA
IDA: Inferred from direct assay
25997655 GOA
involved in toxin metabolic process IDA
IDA: Inferred from direct assay
25997655 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

AS3MT Protein Structure

Methyltransf_31

Methyltransf_31: Methyltransferase domain (70 - 216)

  • 0
  • 100
  • 200
  • 300
  • 375 a.a.
Protein Preferred Names Protein Names

arsenite methyltransferase

  • S-adenosyl-L-methionine:arsenic(III) methyltransferase

Related Diseases

Diseases Alias
Borst-Jadassohn Intraepidermal Carcinoma

  • Intraepidermal Epithelioma Of Jadassohn

  • Bowen'S Disease, Clonal
Schizophrenia

  • SCZD

  • Schizophrenia With Or Without An Affective Disorder

  • Schizophrenia 12

  • Schizophrenia, Susceptibility To

  • Schizophrenia-1

  • Dementia Praecox

  • Schizophrenia 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01052 AS3MT Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta AS3MT VGNC VGNC:69856
Rattus norvegicus AS3MT RGD RGD:621325
Bos taurus AS3MT VGNC VGNC:97241
Felis catus AS3MT VGNC VGNC:59951
Mus musculus AS3MT MGD MGI:1929882
Others AS3MT NCBI