DISP3 - dispatched RND transporter family member 3 Gene

Also Known as PTCHD2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57540

About DISP3

Cytogenetic location: 1p36.22 Genomic coordinates (GRCh38): 1:11,479,155-11,537,551 (from NCBI)

This gene has 3 transcripts (splice variants), 200 orthologues and 10 paralogues. Biased expression in brain (RPKM 1.6), testis (RPKM 1.4) and 1 other tissue.

Summary

Involved in negative regulation of neuron differentiation; positive regulation of lipid metabolic process; and positive regulation of neural precursor cell proliferation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

DISP3 Products (1)

mRNA Protein Name
NM_020780.2 NP_065831.1 protein dispatched homolog 3

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in negative regulation of neuron differentiation IDA
IDA: Inferred from direct assay
25281927 GOA
involved in positive regulation of lipid metabolic process IDA
IDA: Inferred from direct assay
25281927 GOA
involved in positive regulation of neural precursor cell proliferation IDA
IDA: Inferred from direct assay
25281927 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
25281927 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DISP3 Protein Structure

Patched

Patched: Patched family (416 - 698)

MMPL

MMPL: MMPL family (1185 - 1347)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1392 a.a.
Protein Preferred Names Protein Names

protein dispatched homolog 3

  • dispatched 3

Related Diseases

Diseases Alias
Scrotum Melanoma

  • Melanoma Of Scrotum
Cataract 8, Multiple Types

  • Ccv

  • Cataract, Congenital, Volkmann Type

  • CTRCT8

  • Cataract 8 Multiple Types

  • Cataract Congenital Volkmann Type

  • Cutaneous Collagenous Vasculopathy
Anus Benign Neoplasm

  • Anal Neoplasm

  • Anal Tumors

  • Neoplasm Of Anus

  • Anus Neoplasms
Actinomycosis

  • Actinomycetoma

  • Boil

  • Canaliculitis

  • Actinomycotic Infection

  • Actinomycotic Madura Foot

  • Keratoactinomycosis

  • Furuncle

  • Actinomycotic Mycetema

  • Actinomycotic Mycetoma Of Foot

  • Madura Foot Due To Actinomadura

  • Actinomyces Israeli

  • Actinomycetes

  • Anaerobic Actinomyces Infection

  • Actinomycotic Infection Of Unspecified Site

  • Actinomycosis Nos

  • Actinomycotic Node

  • Actinomyces Infection

  • Actinomycotic Mycetoma

  • Mycetoma Due To Filamentous Bacteria
Scrotum Neoplasm

  • Malignant Tumour Of Scrotum

  • Malignant Scrotal Neoplasm

  • Malignant Tumor Of Scrotum

  • Neoplasm Of Scrotum

  • Scrotal Ca

  • Scrotal Tumor

  • Scrotum Cancer

  • Cancer Of Scrotum

  • Malignant Neoplasm Of Scrotum

  • Scrotal Cancer

  • Malignant Scrotal Tumour

  • Malignant Neoplasm Of Skin Of Scrotum

  • Primary Malignant Neoplasm Of Scrotum
Zika Virus Congenital Syndrome

  • Zikv Congenital Infection
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03784 DISP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus DISP3 RGD RGD:1305820
Mus musculus DISP3 MGD MGI:2444403
Felis catus DISP3 VGNC VGNC:61504
Bos taurus DISP3 VGNC VGNC:28076
Canis familiaris DISP3 VGNC VGNC:39968
Macaca mulatta DISP3 VGNC VGNC:106348
Others DISP3 NCBI