ARHGAP20 - Rho GTPase activating protein 20 Gene

Also Known as RARHOGAP

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57569

About ARHGAP20

Cytogenetic location: 11q22.3-q23.1 Genomic coordinates (GRCh38): 11:110,577,043-110,713,189 (from NCBI)

This gene has 7 transcripts (splice variants), 308 orthologues and 1 paralogue. Broad expression in fat (RPKM 5.7), testis (RPKM 5.0) and 20 other tissues.

Summary

The protein encoded by this gene is an activator of RHO-type GTPases, transducing a signal from RAP1 to RHO and impacting neurite outgrowth. [provided by RefSeq, Sep 2016]

ARHGAP20 Products (6)

mRNA Protein Name
NM_001258415.2 NP_001245344.1 rho GTPase-activating protein 20 isoform 2
NM_001258416.2 NP_001245345.1 rho GTPase-activating protein 20 isoform 3
NM_001258417.2 NP_001245346.1 rho GTPase-activating protein 20 isoform 4
NM_001258418.2 NP_001245347.1 rho GTPase-activating protein 20 isoform 4
NM_001384657.1 NP_001371586.1 rho GTPase-activating protein 20 isoform 1
NM_020809.4 NP_065860.2 rho GTPase-activating protein 20 isoform 1

ARHGAP20 Protein Structure

RA

RA: Ras association (RalGDS/AF-6) domain (198 - 273)

RhoGAP

RhoGAP: RhoGAP domain (377 - 523)

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  • 1000
  • 1191 a.a.
Protein Preferred Names Protein Names

rho GTPase-activating protein 20

  • RA and RhoGAP domain containing protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00920 ARHGAP20 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris ARHGAP20 VGNC VGNC:38050
Rattus norvegicus ARHGAP20 RGD RGD:1303160
Macaca mulatta ARHGAP20 VGNC VGNC:69862
Mus musculus ARHGAP20 MGD MGI:2445175
Bos taurus ARHGAP20 VGNC VGNC:26079
Felis catus ARHGAP20 VGNC VGNC:81903
Others ARHGAP20 NCBI