LRFN1 - leucine rich repeat and fibronectin type III domain containing 1 Gene

Also Known as SALM2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57622

About LRFN1

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:39,306,566-39,320,863 (from NCBI)

This gene has 1 transcript (splice variant), 191 orthologues and 25 paralogues. Broad expression in brain (RPKM 2.1), spleen (RPKM 1.1) and 18 other tissues.

Summary

Predicted to be involved in regulation of postsynaptic density assembly. Predicted to be located in plasma membrane. Predicted to be active in cell surface. Predicted to be integral component of postsynaptic density membrane. [provided by Alliance of Genome Resources, Apr 2022]

LRFN1 Products (1)

mRNA Protein Name
NM_020862.2 NP_065913.1 leucine-rich repeat and fibronectin type III domain-containing protein 1 precursor

LRFN1 Protein Structure

LRR_8

LRR_8: Leucine rich repeat (67 - 125)

LRR_8

LRR_8: Leucine rich repeat (163 - 222)

I-set

I-set: Immunoglobulin I-set domain (309 - 387)

fn3

fn3: Fibronectin type III domain (427 - 500)

  • 0
  • 200
  • 400
  • 600
  • 771 a.a.
Protein Preferred Names Protein Names

leucine-rich repeat and fibronectin type III domain-containing protein 1

  • CTC-246B18.8

Related Diseases

Diseases Alias
Epilepsy, Familial Temporal Lobe, 1

  • ETL1

  • Adpeaf

  • Adlte

  • Epilepsy, Partial, With Auditory Features

  • Autosomal Dominant Partial Epilepsy With Auditory Features

  • Epilepsy, Lateral Temporal Lobe, Autosomal Dominant

  • Familial Temporal Lobe Epilepsy 1

  • Partial Epilepsy With Auditory Features

  • Autosomal Dominant Lateral Temporal Lobe Epilepsy

  • Lateral Temporal Lobe Epilepsy Autosomal Dominant

  • Epilepsy, Temporal Lobe, Familial, Type 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07781 LRFN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris LRFN1 VGNC VGNC:42760
Rattus norvegicus LRFN1 RGD RGD:1304707
Bos taurus LRFN1 VGNC VGNC:30975
Mus musculus LRFN1 MGD MGI:2136810
Others LRFN1 NCBI