Slc15a2 - solute carrier family 15 (H+/peptide transporter), member 2 Gene

Mus musculus

Also known as Pept2; 8430408C16Rik

Gene ID: 57738 | Gene type: protein coding

About Slc15a2

Summary

Enables dipeptide transmembrane transporter activity and high-affinity oligopeptide transmembrane transporter activity. Involved in several processes, including dipeptide import across plasma membrane; peptidoglycan transport; and regulation of nucleotide-binding activity oligomerization domain containing signaling pathway. Acts upstream of or within oligopeptide transport. Located in membrane. Is integral component of plasma membrane. Is expressed in several structures, including genitourinary system; integumental system; nervous system; nose; and respiratory system. Orthologous to human SLC15A2 (solute carrier family 15 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc15a2 Products(2)

mRNA	Protein	Name
NM_001145899.2	NP_001139371.2	solute carrier family 15 member 2 isoform 2
NM_021301.4	NP_067276.3	solute carrier family 15 member 2 isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables dipeptide transmembrane transporter activity	IMP IMP: Inferred from mutant phenotype	29784761	MGI
enables high-affinity oligopeptide transmembrane transporter activity	IDA IDA: Inferred from direct assay	11027540	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in dipeptide import across plasma membrane	IMP IMP: Inferred from mutant phenotype	29784761	MGI
involved in dipeptide transport	IMP IMP: Inferred from mutant phenotype	17452417	MGI
acts upstream of or within oligopeptide transport	IDA IDA: Inferred from direct assay	11027540	MGI
involved in peptidoglycan transport	IMP IMP: Inferred from mutant phenotype	29784761	MGI
involved in regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	29784761	MGI
involved in renal absorption	IMP IMP: Inferred from mutant phenotype	17452417	MGI
involved in xenobiotic transport	IMP IMP: Inferred from mutant phenotype	17452417	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in membrane	IDA IDA: Inferred from direct assay	11027540	MGI
located in plasma membrane	IDA IDA: Inferred from direct assay	11027540	MGI
located in plasma membrane	IMP IMP: Inferred from mutant phenotype	29784761	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

solute carrier family 15 member 2

kidney H(+)/peptide cotransporter	peptide transporter 2
proton-dependent high affinity oligopeptide transporter PepT2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13013	SLC15A2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc15a2	NCBI	NCBI:6565

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