Tesc - tescalcin Gene

Also Known as TE-1; 1010001A17Rik; 2410011K10Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 57816

Summary

Enables metal ion binding activity; Phosphatase Inhibitor activity; and protein homodimerization activity. Acts upstream of or within male gonad development and megakaryocyte differentiation. Located in several cellular components, including lamellipodium; nucleus; and ruffle. Is expressed in several structures, including adrenal gland; brain; gonad; metanephros; and sensory organ. Orthologous to human TESC (tescalcin). [provided by Alliance of Genome Resources, Apr 2022]

Tesc Products (1)

mRNA Protein Name
NM_021344.4 NP_067319.2 calcineurin B homologous protein 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables calcium ion binding IDA
IDA: Inferred from direct assay
14661968 MGI
enables magnesium ion binding IDA
IDA: Inferred from direct assay
14661968 MGI
enables phosphatase inhibitor activity IDA
IDA: Inferred from direct assay
14661968 MGI
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
14661968 MGI
Biological Process GO Annotation Evidence References Source
involved in male gonad development IEP
IEP: Inferred from expression pattern
11145610 MGI
NOT involved in megakaryocyte development IMP
IMP: Inferred from mutant phenotype
22285131 MGI
involved in megakaryocyte differentiation IEP
IEP: Inferred from expression pattern
17717601 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
14661968 MGI
located in lamellipodium IDA
IDA: Inferred from direct assay
14661968 MGI
located in nucleus IDA
IDA: Inferred from direct assay
14661968 MGI
located in ruffle IDA
IDA: Inferred from direct assay
14661968 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

calcineurin B homologous protein 3

  • CHP3

  • TSC

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14379 TESC Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tesc NCBI NCBI:54997