2. Gene
  3. CACTIN - cactin, spliceosome C complex subunit Gene

CACTIN - cactin, spliceosome C complex subunit Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as fSAPc; C19orf29; NY-REN-24

Gene ID: 58509 | Gene type: protein coding

About CACTIN

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:3,610,645-3,626,790 (from NCBI)

This gene has 10 transcripts (splice variants), 198 orthologues and 2 paralogues. Ubiquitous expression in spleen (RPKM 5.5), testis (RPKM 4.7) and 25 other tissues.

Summary

Enables RNA binding activity. Involved in several processes, including cellular response to cytokine stimulus; negative regulation of cytokine production; and negative regulation of signal transduction. Located in cytosol and nuclear speck. Part of catalytic step 2 spliceosome. [provided by Alliance of Genome Resources, Apr 2022]

CACTIN Products(2)

mRNA Protein Name
NM_001080543.2 NP_001074012.1 cactin
NM_021231.2 NP_067054.1 cactin

CACTIN Protein Structure

Cactin_mid

Cactin_mid: Conserved mid region of cactin (201 - 390)

CactinC_cactus

CactinC_cactus: Cactus-binding C-terminus of cactin protein (566 - 690)

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  • 867 a.a.
Protein Preferred Names Protein Names

cactin

NY REN 24 antigen

Related Diseases

Diseases Alias
Nephrolithiasis/Osteoporosis, Hypophosphatemic, 2

Hypophosphatemic Nephrolithiasis/Osteoporosis 2

NPHLOP2

Nephrolithiasis-Osteoporosis, Hypophosphatemic, 2

Nephrolithiasis/Osteoporosis, Hypophosphatemic, Type 2
Gluten Allergy

Allergy To Gluten

Gluten Allergic Reaction
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01816 CACTIN Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus CACTIN RGD RGD:1563634
Bos taurus CACTIN VGNC VGNC:58364
Felis catus CACTIN VGNC VGNC:60313
Mus musculus CACTIN MGD MGI:1917562
Canis familiaris CACTIN VGNC VGNC:38653
Macaca mulatta CACTIN VGNC VGNC:108486