Elp2 - elongator acetyltransferase complex subunit 2 Gene

Also Known as Epl2; StIP1; Statip1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 58523

Summary

Enables protein kinase binding activity. Acts upstream of or within regulation of receptor signaling pathway via JAK-STAT. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of elongator holoenzyme complex and transcription elongation factor complex. Is expressed in central nervous system; liver; and retina nuclear layer. Used to study autism spectrum disorder and intellectual disability. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human ELP2 (elongator acetyltransferase complex subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Elp2 Products (2)

mRNA Protein Name
NM_001360909.1 NP_001347838.1 elongator complex protein 2 isoform 2
NM_021448.2 NP_067423.2 elongator complex protein 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein kinase binding IDA
IDA: Inferred from direct assay
10954736 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within regulation of receptor signaling pathway via JAK-STAT IDA
IDA: Inferred from direct assay
10954736 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

elongator complex protein 2

  • STAT3-interacting protein 1

  • elongation protein 2 homolog

  • signal transducer and activator of transcription 3 interacting protein 1

  • signal transducer and activator of transcription interacting protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04329 ELP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Elp2 NCBI NCBI:55250