2. Gene
  3. Htr3b - 5-hydroxytryptamine receptor 3B Gene

Htr3b - 5-hydroxytryptamine receptor 3B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 58963 | Gene type: protein coding

About Htr3b

Summary

Predicted to enable serotonin-gated cation-selective channel activity. Involved in cellular response to growth factor stimulus and positive regulation of ion transmembrane transporter activity. Located in axon and neuronal cell body. Human ortholog(s) of this gene implicated in alcohol use disorder and mental depression. Orthologous to human HTR3B (5-hydroxytryptamine receptor 3B). [provided by Alliance of Genome Resources, Apr 2022]

Htr3b Products(1)

mRNA Protein Name
NM_022189.1 NP_071525.1 5-hydroxytryptamine receptor 3B precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables serotonin-gated monoatomic cation channel activity IDA
IDA: Inferred from direct assay
10854267 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to growth factor stimulus IEP
IEP: Inferred from expression pattern
10854267 RGD
involved in positive regulation of ion transmembrane transporter activity IDA
IDA: Inferred from direct assay
10854267 RGD
Cellular Component GO Annotation Evidence Reference Source
located in axon IDA
IDA: Inferred from direct assay
17650111 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
17650111 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

5-hydroxytryptamine receptor 3B

5-HT-3B

5-HT3-B

5-HT3B

5-hydroxytryptamine (serotonin) receptor 3B, ionotropic

serotonin receptor 3B

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06473 HTR3B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Htr3b NCBI NCBI:9177