Nrip2 - nuclear receptor interacting protein 2 Gene

Also Known as NIX1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 60345

Summary

Predicted to enable aspartic-type endopeptidase activity. Acts upstream of or within Notch signaling pathway and negative regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in brain; heart; hypothalamus mantle layer; and telencephalon. Orthologous to human NRIP2 (nuclear receptor interacting protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Nrip2 Products (4)

mRNA Protein Name
NM_001162858.2 NP_001156330.1 nuclear receptor-interacting protein 2 isoform 1
NM_001411379.1 NP_001398308.1 nuclear receptor-interacting protein 2 isoform 2
NM_001411380.1 NP_001398309.1 nuclear receptor-interacting protein 2 isoform 3
NM_021717.3 NP_068363.2 nuclear receptor-interacting protein 2 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10860982 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within Notch signaling pathway IDA
IDA: Inferred from direct assay
23117660 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
10860982 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
10860982 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear receptor-interacting protein 2

  • neuronal interacting factor 1

  • neuronal-interacting factor X 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09572 NRIP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nrip2 NCBI NCBI:83714