2. Gene
  3. Nrip2 - nuclear receptor interacting protein 2 Gene

Nrip2 - nuclear receptor interacting protein 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as NIX1

Gene ID: 60345 | Gene type: protein coding

About Nrip2

Summary

Predicted to enable aspartic-type endopeptidase activity. Acts upstream of or within Notch signaling pathway and negative regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in brain; heart; hypothalamus mantle layer; and telencephalon. Orthologous to human NRIP2 (nuclear receptor interacting protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Nrip2 Products(4)

mRNA Protein Name
NM_001162858.2 NP_001156330.1 nuclear receptor-interacting protein 2 isoform 1
NM_001411379.1 NP_001398308.1 nuclear receptor-interacting protein 2 isoform 2
NM_001411380.1 NP_001398309.1 nuclear receptor-interacting protein 2 isoform 3
NM_021717.3 NP_068363.2 nuclear receptor-interacting protein 2 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
10860982 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within Notch signaling pathway IDA
IDA: Inferred from direct assay
23117660 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
10860982 MGI
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
10860982 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear receptor-interacting protein 2

neuronal interacting factor 1

neuronal-interacting factor X 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09572 NRIP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nrip2 NCBI NCBI:83714