CDH26 - cadherin 26 Gene

Also Known as VR20

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 60437

About CDH26

Cytogenetic location: 20q13.33 Genomic coordinates (GRCh38): 20:59,958,423-60,035,934 (from NCBI)

This gene has 7 transcripts (splice variants), 185 orthologues and 33 paralogues. Biased expression in prostate (RPKM 2.7), urinary bladder (RPKM 1.4) and 10 other tissues.

Summary

This gene encodes a member of the Cadherin protein family. Cadherins are a family of calcium-dependent adhesion molecules that mediate cell-cell adhesion in all solid tissues and modulate a wide variety of processes, including cell polarization, migration and differentiation. Cadherin domains occur as repeats in the extracellular region and are thought to contribute to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. This protein is expressed in gastrointestinal epithelial cells and may be upregulated during allergic inflammation. This protein interacts with alpha integrins and may also be involved in leukocyte migration and adhesion. [provided by RefSeq, Jan 2017]

CDH26 Products (3)

mRNA Protein Name
NM_001348204.2 NP_001335133.1 cadherin-like protein 26 isoform c
NM_021810.6 NP_068582.2 cadherin-like protein 26 isoform b
NM_177980.4 NP_817089.1 cadherin-like protein 26 isoform a precursor

CDH26 Protein Structure

Cadherin

Cadherin: Cadherin domain (170 - 266)

Cadherin

Cadherin: Cadherin domain (280 - 386)

Cadherin

Cadherin: Cadherin domain (406 - 486)

  • 0
  • 200
  • 400
  • 600
  • 832 a.a.
Protein Preferred Names Protein Names

cadherin-like protein 26

  • cadherin-like 26

Related Diseases

Diseases Alias
Eosinophilic Gastritis
  • Eosinophilic Enteropathy

Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip/Palate Syndrome 1
  • Eec Syndrome

  • Rudiger Syndrome 1

  • Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip-Palate Syndrome 1

  • EEC1

  • Eec Syndrome 1

  • Eec Syndrome-1

  • Walker-Clodius Syndrome

  • Ectrodactyly-Ectodermal Dysplasia-Cleft Lip/Palate Syndrome

  • Eec

  • Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip-Palate Syndrome

  • Ectrodactyly-Ectodermal Dysplasia-Clefting Syndrome

  • Ectrodactyly-Cleft Lip/Palate Syndrome

  • Ectrodactyly-Ectodermal Dysplasia-Cleft Lip/Cleft Palate

  • Ectrodactyly-Ectodermal Dysplasia-Clefting Syndrome

  • Ectrodactyly, Ectodermal Dysplasia, Clefting Syndrome

  • Ectrodactyly-Cleft Lip-Palate Syndrome

  • Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip/Palate Syndrome

Ross River Fever
  • Ross River Virus Disease

  • Ross River Virus Infection

Esophagitis, Eosinophilic, 1
  • Eosinophilic Esophagitis

  • EOE1

  • Esophagitis, Eosinophilic

  • Ee

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Canis familiaris CDH26 VGNC VGNC:54617
Macaca mulatta CDH26 VGNC VGNC:70955
Bos taurus CDH26 VGNC VGNC:27102
Felis catus CDH26 VGNC VGNC:60682
Rattus norvegicus CDH26 RGD RGD:1311632
Mus musculus CDH26 MGD MGI:2685856
Others CDH26 NCBI