CDH26 - cadherin 26 Gene
Also Known as VR20
Species: Homo sapiens
About CDH26
This gene has 7 transcripts (splice variants), 185 orthologues and 33 paralogues. Biased expression in prostate (RPKM 2.7), urinary bladder (RPKM 1.4) and 10 other tissues.
Summary
This gene encodes a member of the Cadherin protein family. Cadherins are a family of calcium-dependent adhesion molecules that mediate cell-cell adhesion in all solid tissues and modulate a wide variety of processes, including cell polarization, migration and differentiation. Cadherin domains occur as repeats in the extracellular region and are thought to contribute to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. This protein is expressed in gastrointestinal epithelial cells and may be upregulated during allergic inflammation. This protein interacts with alpha integrins and may also be involved in leukocyte migration and adhesion. [provided by RefSeq, Jan 2017]
CDH26 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001348204.2 | NP_001335133.1 | cadherin-like protein 26 isoform c |
| NM_021810.6 | NP_068582.2 | cadherin-like protein 26 isoform b |
| NM_177980.4 | NP_817089.1 | cadherin-like protein 26 isoform a precursor |
CDH26 Protein Structure
Cadherin: Cadherin domain (170 - 266)
Cadherin: Cadherin domain (280 - 386)
Cadherin: Cadherin domain (406 - 486)
- 0
- 200
- 400
- 600
- 832 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
cadherin-like protein 26 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Eosinophilic Gastritis |
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| Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip/Palate Syndrome 1 |
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| Ross River Fever |
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| Esophagitis, Eosinophilic, 1 |
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Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Canis familiaris | CDH26 | VGNC | VGNC:54617 |
| Macaca mulatta | CDH26 | VGNC | VGNC:70955 |
| Bos taurus | CDH26 | VGNC | VGNC:27102 |
| Felis catus | CDH26 | VGNC | VGNC:60682 |
| Rattus norvegicus | CDH26 | RGD | RGD:1311632 |
| Mus musculus | CDH26 | MGD | MGI:2685856 |
| Others | CDH26 | NCBI |