CDH26 - cadherin 26 Gene

Homo sapiens

Also known as VR20

Gene ID: 60437 | Gene type: protein coding

About CDH26

Cytogenetic location: 20q13.33 Genomic coordinates (GRCh38): 20:59,958,423-60,035,934 (from NCBI)

This gene has 7 transcripts (splice variants), 185 orthologues and 33 paralogues. Biased expression in prostate (RPKM 2.7), urinary bladder (RPKM 1.4) and 10 other tissues.

Summary

This gene encodes a member of the cadherin protein family. Cadherins are a family of calcium-dependent adhesion molecules that mediate cell-cell adhesion in all solid tissues and modulate a wide variety of processes, including cell polarization, migration and differentiation. Cadherin domains occur as repeats in the extracellular region and are thought to contribute to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. This protein is expressed in gastrointestinal epithelial cells and may be upregulated during allergic inflammation. This protein interacts with alpha integrins and may also be involved in leukocyte migration and adhesion. [provided by RefSeq, Jan 2017]

CDH26 Products(3)

mRNA	Protein	Name
NM_001348204.2	NP_001335133.1	cadherin-like protein 26 isoform c
NM_021810.6	NP_068582.2	cadherin-like protein 26 isoform b
NM_177980.4	NP_817089.1	cadherin-like protein 26 isoform a precursor

CDH26 Protein Structure

Cadherin

0
200
400
600
832 a.a.

Protein Preferred Names

Protein Names

cadherin-like protein 26

cadherin-like 26

Related Diseases

Diseases

Alias

Eosinophilic Gastritis

Eosinophilic Enteropathy

Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip/Palate Syndrome 1

Eec Syndrome	Rudiger Syndrome 1
Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip-Palate Syndrome 1	EEC1
Eec Syndrome 1	Eec Syndrome-1
Walker-Clodius Syndrome	Ectrodactyly-Ectodermal Dysplasia-Cleft Lip/Palate Syndrome
Eec	Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip-Palate Syndrome
Ectrodactyly-Ectodermal Dysplasia-Clefting Syndrome	Ectrodactyly-Cleft Lip/Palate Syndrome
Ectrodactyly-Ectodermal Dysplasia-Cleft Lip/Cleft Palate	Ectrodactyly-Ectodermal Dysplasia-Clefting Syndrome
Ectrodactyly, Ectodermal Dysplasia, Clefting Syndrome	Ectrodactyly-Cleft Lip-Palate Syndrome
Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip/Palate Syndrome

Ross River Fever

Ross River Virus Disease

Ross River Virus Infection

Esophagitis, Eosinophilic, 1

Eosinophilic Esophagitis	EOE1
Esophagitis, Eosinophilic	Ee

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02335	CDH26 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	CDH26	VGNC	VGNC:54617
Macaca mulatta	CDH26	VGNC	VGNC:70955
Bos taurus	CDH26	VGNC	VGNC:27102
Felis catus	CDH26	VGNC	VGNC:60682
Rattus norvegicus	CDH26	RGD	RGD:1311632
Mus musculus	CDH26	MGD	MGI:2685856

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