Trp53inp1 - transformation related protein 53 inducible nuclear protein 1 Gene

Also Known as SIP; Teap; SIP18; SIP27; Stinp; Tp53inp1; p53DINP1; 2700057G22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 60599

Summary

Enables antioxidant activity. Involved in several processes, including negative regulation of fibroblast proliferation; negative regulation of myofibroblast differentiation; and regulation of gene expression. Acts upstream of or within several processes, including cellular response to ethanol; cellular response to hydroperoxide; and cellular response to methyl methanesulfonate. Located in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Used to study abdominal obesity-metabolic syndrome 1. Orthologous to human TP53INP1 (tumor protein p53 inducible nuclear protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Trp53inp1 Products (2)

mRNA Protein Name
NM_001199105.2 NP_001186034.1 tumor protein p53-inducible nuclear protein 1 isoform 2
NM_021897.4 NP_068697.1 tumor protein p53-inducible nuclear protein 1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables antioxidant activity IMP
IMP: Inferred from mutant phenotype
19118006 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to UV IDA
IDA: Inferred from direct assay
11557757 MGI
acts upstream of or within cellular response to ethanol IDA
IDA: Inferred from direct assay
11557757 MGI
acts upstream of or within cellular response to hydroperoxide IDA
IDA: Inferred from direct assay
11557757 MGI
acts upstream of or within cellular response to methyl methanesulfonate IDA
IDA: Inferred from direct assay
11557757 MGI
involved in negative regulation of cell migration IMP
IMP: Inferred from mutant phenotype
21339733 MGI
involved in negative regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
19118006 MGI
involved in negative regulation of fibroblast proliferation IMP
IMP: Inferred from mutant phenotype
26589288 MGI
involved in negative regulation of gene expression IMP
IMP: Inferred from mutant phenotype
26589288 MGI
involved in negative regulation of myofibroblast differentiation IMP
IMP: Inferred from mutant phenotype
26589288 MGI
acts upstream of or within positive regulation of apoptotic process IDA
IDA: Inferred from direct assay
11557757 MGI
involved in positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
26589288 MGI
acts upstream of or within response to heat IDA
IDA: Inferred from direct assay
11557757 MGI
Cellular Component GO Annotation Evidence References Source
NOT located in nucleolus IDA
IDA: Inferred from direct assay
11557757 MGI
located in nucleus IDA
IDA: Inferred from direct assay
11557757 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tumor protein p53-inducible nuclear protein 1

  • p53-dependent damage-inducible nuclear protein 1

  • stress induced protein

  • thymus-expressed acidic protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS28596 Tp53inp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown