ADORA3 - adenosine A3 receptor Gene

Sus scrofa

Gene ID: 606753 | Gene type: protein coding

About ADORA3

Primary_assembly 4: 108,854,357-108,873,925 forward strand.Sscrofa11.1:CM000815.5

This gene has 6 transcripts (splice variants), 78 orthologues and 14 paralogues. Biased expression in spleen (RPKM 83.), lung (RPKM 32.6) and 3 other tissues.

Summary

This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors involved in a variety of intracellular signaling pathways and physiological functions. Studies of orthologous proteins suggest that the receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it may have neuroprotective and neurodegenerative effects, and it may also mediate cell proliferation and cell death. This gene shares its 3' terminal exon with some transcripts from overlapping GeneID:104564308, which encodes a transmembrane and immunoglobulin domain-containing protein. [provided by RefSeq, Nov 2014]

ADORA3 Products(1)

mRNA	Protein	Name
NM_001243435.2	NP_001230364.2	adenosine A3 receptor

ADORA3 Protein Structure

7tmA_Adenosine_R_A3

0
100
200
300
318 a.a.

Protein Preferred Names

Protein Names

adenosine A3 receptor

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00400	ADORA3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS00401	Adora3 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS00402	ADORA3 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	ADORA3	NCBI	NCBI:140

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