2. Gene
  3. CELF6 - CUGBP Elav-like family member 6 Gene

CELF6 - CUGBP Elav-like family member 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as BRUNOL6

Gene ID: 60677 | Gene type: protein coding

About CELF6

Cytogenetic location: 15q23 Genomic coordinates (GRCh38): 15:72,284,727-72,320,157 (from NCBI)

This gene has 5 transcripts (splice variants), 210 orthologues and 6 paralogues. Ubiquitous expression in brain (RPKM 5.2), ovary (RPKM 3.9) and 24 other tissues.

Summary

Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010]

CELF6 Products(3)

mRNA Protein Name
NM_001172684.2 NP_001166155.1 CUGBP Elav-like family member 6 isoform 2
NM_001172685.2 NP_001166156.1 CUGBP Elav-like family member 6 isoform 3
NM_052840.5 NP_443072.3 CUGBP Elav-like family member 6 isoform 1

CELF6 Protein Structure

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (48 - 115)

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (136 - 198)

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (398 - 467)

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  • 481 a.a.
Protein Preferred Names Protein Names

CUGBP Elav-like family member 6

Bruno -like 6, RNA binding protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02464 CELF6 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus CELF6 MGD MGI:1923433
Rattus norvegicus CELF6 RGD RGD:1310451