Slc6a17 - solute carrier family 6 member 17 Gene

Also Known as Ntt4

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 613226

Summary

Predicted to enable symporter activity. Involved in neutral amino acid transport. Located in synaptic vesicle. Is active in GABA-ergic synapse and glutamatergic synapse. Is integral component of synaptic vesicle membrane. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human SLC6A17 (solute carrier family 6 member 17). [provided by Alliance of Genome Resources, Apr 2022]

Slc6a17 Products (1)

mRNA Protein Name
NM_001033079.2 NP_001028251.1 sodium-dependent neutral amino acid transporter SLC6A17

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in L-leucine transport IDA
IDA: Inferred from direct assay
18768736 RGD
involved in alanine transport IDA
IDA: Inferred from direct assay
18768736 RGD
involved in glycine transport IDA
IDA: Inferred from direct assay
18768736 RGD
involved in neutral amino acid transport IDA
IDA: Inferred from direct assay
19147495 RGD
involved in proline transport IDA
IDA: Inferred from direct assay
18768736 RGD
involved in protein catabolic process IDA
IDA: Inferred from direct assay
19147495 RGD
involved in protein catabolic process IMP
IMP: Inferred from mutant phenotype
19147495 RGD
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
10103130 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
10103130 RGD
is active in synapse IDA
IDA: Inferred from direct assay
19147495 RGD
is active in synapse IMP
IMP: Inferred from mutant phenotype
19147495 RGD
located in synaptic vesicle IDA
IDA: Inferred from direct assay
18768736 RGD
is active in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
10103130 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium-dependent neutral amino acid transporter SLC6A17

  • orphan sodium- and chloride-dependent neurotransmitter transporter NTT4

  • sodium-dependent neurotransmitter transporter NTT4

  • solute carrier family 6 (neurotransmitter transporter), member 17

  • solute carrier family 6 (neutral amino acid transporter), membe

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13303 SLC6A17 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc6a17 NCBI NCBI:388662