Majin - membrane anchored junction protein Gene

Also Known as 1700123I01Rik

Species: Mus musculus

Gene Type: protein coding

Gene ID: 622554

Summary

Predicted to enable DNA binding activity. Involved in homologous chromosome pairing at meiosis and meiotic attachment of telomere to nuclear envelope. Located in chromosome, telomeric region. Is integral component of nuclear inner membrane. Orthologous to human MAJIN (membrane anchored junction protein). [provided by Alliance of Genome Resources, Apr 2022]

Majin Products (3)

mRNA	Protein	Name
NM_001165919.2	NP_001159391.1	membrane-anchored junction protein isoform 1
NM_001377074.1	NP_001364003.1	membrane-anchored junction protein isoform 2
NM_001377075.1	NP_001364004.1	membrane-anchored junction protein isoform 3

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	30718482	MGI

Biological Process GO Annotation	Evidence	References	Source
acts upstream of or within double-strand break repair involved in meiotic recombination	IGI IGI: Inferred from genetic interaction	30718482	MGI
acts upstream of or within homologous chromosome pairing at meiosis	IGI IGI: Inferred from genetic interaction	30718482	MGI
involved in homologous chromosome pairing at meiosis	IMP IMP: Inferred from mutant phenotype	26548954	MGI
acts upstream of or within meiotic attachment of telomere to nuclear envelope	IGI IGI: Inferred from genetic interaction	30718482	MGI
involved in meiotic attachment of telomere to nuclear envelope	IMP IMP: Inferred from mutant phenotype	26548954	MGI
acts upstream of or within meiotic cell cycle process	IMP IMP: Inferred from mutant phenotype	34326397	MGI
involved in meiotic telomere clustering	IMP IMP: Inferred from mutant phenotype	26548954	MGI
acts upstream of or within oogenesis	IMP IMP: Inferred from mutant phenotype	34326397	MGI
acts upstream of or within spermatogenesis	IMP IMP: Inferred from mutant phenotype	34326397	MGI

Cellular Component GO Annotation	Evidence	References	Source
located in chromosome, telomeric region	IDA IDA: Inferred from direct assay	26548954	MGI
located in nuclear envelope	IDA IDA: Inferred from direct assay	28031483	MGI
located in nuclear inner membrane	IDA IDA: Inferred from direct assay	26548954	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
membrane-anchored junction protein

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07988	MAJIN Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Majin	NCBI	NCBI:283129