Angptl8 - angiopoietin-like 8 Gene

Also Known as Rifl; Gm6484; EG624219

Species: Mus musculus

Gene Type: protein coding
Gene ID: 624219

Summary

Predicted to enable hormone activity. Involved in several processes, including regulation of lipid metabolic process; regulation of lipoprotein metabolic process; and triglyceride homeostasis. Acts upstream of or within cell maturation and fat cell differentiation. Predicted to be active in extracellular region. Orthologous to human ANGPTL8 (angiopoietin like 8). [provided by Alliance of Genome Resources, Apr 2022]

Angptl8 Products (1)

mRNA Protein Name
NM_001080940.1 NP_001074409.1 angiopoietin-like protein 8 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within cell maturation IMP
IMP: Inferred from mutant phenotype
22569073 MGI
involved in cellular lipid metabolic process IMP
IMP: Inferred from mutant phenotype
22809513 MGI
acts upstream of or within fat cell differentiation IMP
IMP: Inferred from mutant phenotype
22569073 MGI
involved in fat cell differentiation IMP
IMP: Inferred from mutant phenotype
24043787 MGI
NOT involved in glucose metabolic process IMP
IMP: Inferred from mutant phenotype
24043787 MGI
acts upstream of or within regulation of lipid metabolic process IMP
IMP: Inferred from mutant phenotype
22569073 MGI
involved in regulation of lipid metabolic process IMP
IMP: Inferred from mutant phenotype
24043787 MGI
involved in regulation of lipoprotein metabolic process IMP
IMP: Inferred from mutant phenotype
24043787 MGI
involved in triglyceride homeostasis IMP
IMP: Inferred from mutant phenotype
22809513 MGI
NOT involved in type B pancreatic cell proliferation IDA
IDA: Inferred from direct assay
24353178 MGI
NOT involved in type B pancreatic cell proliferation IMP
IMP: Inferred from mutant phenotype
25417115 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

angiopoietin-like protein 8

  • betatrophin

  • hepatocellular carcinoma-associated protein TD26 homolog

  • lipasin

  • refeeding-induced fat and liver protein

Recombinant Angptl8 Proteins

Cat. No. Product Name Accession Purity
HY-P700561 ANGPTL8/Angiopoietin-like 8 Protein, Mouse (P. pastoris, His) Q8R1L8 (V16-A198) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P700633 ANGPTL8/Angiopoietin-like 8 Protein, Mouse (H40A, Q44A, Q47A, His) Q8R1L8 (V16-A198, H40A, Q44A, Q47A) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990336 Anti-ANGPTL8 Antibody Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Angptl8 NCBI NCBI:55908