Fgf14 - fibroblast growth factor 14 Gene

Also Known as Fhf4; FGF-14

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 63851

Summary

Enables growth factor activity. Acts upstream of or within several processes, including positive regulation of high voltage-gated Calcium Channel activity; regulation of postsynaptic membrane potential; and regulation of synaptic vesicle recycling. Predicted to be located in cytosol. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 27. Orthologous to human FGF14 (Fibroblast Growth Factor 14). [provided by Alliance of Genome Resources, Apr 2022]

Fgf14 Products (2)

mRNA Protein Name
NM_001411965.1 NP_001398894.1 fibroblast growth factor 14 isoform 2
NM_022223.3 NP_071559.2 fibroblast growth factor 14 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables growth factor activity IDA
IDA: Inferred from direct assay
1824921 RGD
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of high voltage-gated calcium channel activity IMP
IMP: Inferred from mutant phenotype
23831029 RGD
acts upstream of or within regulation of postsynaptic membrane potential IDA
IDA: Inferred from direct assay
23831029 RGD
acts upstream of or within regulation of synaptic plasticity IMP
IMP: Inferred from mutant phenotype
23831029 RGD
acts upstream of or within regulation of synaptic vesicle recycling IMP
IMP: Inferred from mutant phenotype
23831029 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fibroblast growth factor 14

  • FGF homologus factor 4b

  • fibroblast growth factor homologous factor 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04891 FGF14 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174707 Human FGF14 mRNA / Unkown
HY-RS18818 Fgf14 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25308 Fgf14 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fgf14 NCBI NCBI:2259