Smc1a - structural maintenance of chromosomes 1A Gene

Also Known as SB1.8; SMC-1A; Smc1l1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 63996

Summary

Predicted to enable several functions, including chromatin binding activity; mediator complex binding activity; and protein heterodimerization activity. Involved in meiotic cell cycle. Predicted to be located in several cellular components, including kinetochore; mitotic spindle pole; and nuclear lumen. Predicted to be part of meiotic cohesin complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 2 and developmental and epileptic encephalopathy. Orthologous to human SMC1A (structural maintenance of chromosomes 1A). [provided by Alliance of Genome Resources, Apr 2022]

Smc1a Products (1)

mRNA Protein Name
NM_031683.2 NP_113871.2 structural maintenance of chromosomes protein 1A

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in meiotic cell cycle IDA
IDA: Inferred from direct assay
10652260 RGD
involved in meiotic cell cycle IEP
IEP: Inferred from expression pattern
10652260 RGD
Cellular Component GO Annotation Evidence References Source
located in lateral element IDA
IDA: Inferred from direct assay
10652260 RGD
located in nucleoplasm IDA
IDA: Inferred from direct assay
10652260 RGD
located in synaptonemal complex IDA
IDA: Inferred from direct assay
10652260 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

structural maintenance of chromosomes protein 1A

  • DXhXs423e

  • SMC (segregation of mitotic chromosomes 1)-like 1

  • SMC protein 1A

  • SMC-like 1

  • SMC-protein

  • segregation of mitotic chromosomes-like 1

  • structural maintenance of chromosomes 1 like 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13416 SMC1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22809 Smc1a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Smc1a NCBI NCBI:8243