Slc29a1 - solute carrier family 29 member 1 Gene

Rattus norvegicus

Also known as ENT1; rENT1

Gene ID: 63997 | Gene type: protein coding

About Slc29a1

Summary

Enables nucleoside transmembrane transporter activity. Involved in several processes, including cellular response to glucose stimulus; lactation; and uridine transport. Located in plasma membrane. Is active in postsynapse and presynapse. Used to study brain ischemia. Orthologous to human SLC29A1 (solute carrier family 29 member 1 (Augustine blood group)). [provided by Alliance of Genome Resources, Apr 2022]

Slc29a1 Products(1)

mRNA	Protein	Name
NM_031684.2	NP_113872.1	equilibrative nucleoside transporter 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables nucleoside transmembrane transporter activity	IDA IDA: Inferred from direct assay	9353301	RGD
enables uridine transmembrane transporter activity	IDA IDA: Inferred from direct assay	9353301	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to glucose stimulus	IEP IEP: Inferred from expression pattern	17941087	RGD
involved in cellular response to hypoxia	IEP IEP: Inferred from expression pattern	10646513	RGD
involved in excitatory postsynaptic potential	IMP IMP: Inferred from mutant phenotype	12611914	RGD
involved in lactation	IEP IEP: Inferred from expression pattern	19702690	RGD
involved in nucleoside transmembrane transport	IDA IDA: Inferred from direct assay	9353301	RGD
involved in nucleoside transport	IDA IDA: Inferred from direct assay	9353301	RGD
involved in uridine transmembrane transport	IDA IDA: Inferred from direct assay	9353301	RGD
involved in uridine transmembrane transport	IMP IMP: Inferred from mutant phenotype	19135251	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in basolateral plasma membrane	IDA IDA: Inferred from direct assay	23639800	RGD
is active in postsynapse	IDA IDA: Inferred from direct assay	16226730	RGD
is active in presynapse	IDA IDA: Inferred from direct assay	16226730	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

equilibrative nucleoside transporter 1

NBMPR-sensitive equilibrative nucleoside transporter	equilibrative NBMPR-sensitive nucleoside transporter
equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter	nucleoside transporter, es-type
solute carrier family 29 (equil

Related Agents

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-116927	KW-7158		/	Phase 2

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13153	SLC29A1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS22039	Slc29a1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc29a1	NCBI	NCBI:2030

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