Smoc1 - SPARC related modular calcium binding 1 Gene

Also Known as SRG; 2600002F22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 64075

Summary

Enables extracellular matrix binding activity. Involved in eye development and limb development. Acts upstream of or within extracellular matrix organization and positive regulation of cell-substrate adhesion. Located in basement membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hindlimb; and sensory organ. Used to study microphthalmia with limb anomalies. Human ortholog(s) of this gene implicated in microphthalmia with limb anomalies. Orthologous to human SMOC1 (SPARC related modular calcium binding 1). [provided by Alliance of Genome Resources, Apr 2022]

Smoc1 Products (2)

mRNA Protein Name
NM_001146217.1 NP_001139689.1 SPARC-related modular calcium-binding protein 1 isoform 1 precursor
NM_022316.2 NP_071711.2 SPARC-related modular calcium-binding protein 1 isoform 2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables extracellular matrix binding IDA
IDA: Inferred from direct assay
18757743 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within extracellular matrix organization IDA
IDA: Inferred from direct assay
18757743 MGI
involved in eye development IMP
IMP: Inferred from mutant phenotype
21194678 MGI
involved in limb development IMP
IMP: Inferred from mutant phenotype
21194678 MGI
acts upstream of or within positive regulation of cell-substrate adhesion IDA
IDA: Inferred from direct assay
18757743 MGI
Cellular Component GO Annotation Evidence References Source
located in basement membrane IDA
IDA: Inferred from direct assay
18757743 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SPARC-related modular calcium-binding protein 1

  • SMOC-1

  • SPARC-related gene protein

  • SPARC-related protein

  • secreted modular calcium binding protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13444 SMOC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17993 Smoc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24464 Smoc1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Smoc1 NCBI NCBI:64093