1. Gene
  2. FN3K - fructosamine 3 kinase Gene

FN3K - fructosamine 3 kinase Gene

Homo sapiens
Gene ID: 64122 | Gene type: protein coding

About FN3K

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:82,735,615-82,751,196 (from NCBI)

This gene has 5 transcripts (splice variants), 188 orthologues and 1 paralogue. Broad expression in kidney (RPKM 47.7), brain (RPKM 22.0) and 20 other tissues.

Summary

A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way, fructosamines, are less active or functional. This gene encodes an Enzyme which catalyzes the phosphorylation of fructosamines which may result in deglycation. [provided by RefSeq, Feb 2012]

FN3K Products(1)

mRNA Protein Name
NM_022158.4 NP_071441.1 fructosamine-3-kinase

FN3K Protein Structure

Fructosamin_kin

Fructosamin_kin: Fructosamine kinase (21 - 308)

  • 0
  • 100
  • 200
  • 309 a.a.
Protein Preferred Names Protein Names

fructosamine-3-kinase

protein-psicosamine 3-kinase FN3K

Recombinant FN3K Proteins

Cat. No. Product Name Accession Purity
HY-P79361 Fructosamine-3-kinase/FN3K Protein, Human (His) Q9H479 (E2-K309) ≥95%

Orthologs Information

Species Symbol Source ID
Mus musculus FN3K MGD MGI:1926834
Macaca mulatta FN3K VGNC VGNC:72569
Felis catus FN3K VGNC VGNC:62315
Canis familiaris FN3K VGNC VGNC:54306
Rattus norvegicus FN3K RGD RGD:1559983
Bos taurus FN3K VGNC VGNC:29057