2. Gene
  3. Sptan1 - spectrin, alpha, non-erythrocytic 1 Gene

Sptan1 - spectrin, alpha, non-erythrocytic 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as A2a; IPF; Spna2

Gene ID: 64159 | Gene type: protein coding

About Sptan1

Summary

Enables spectrin binding activity and syntaxin binding activity. Involved in actin Cytoskeleton reorganization. Located in plasma membrane. Part of protein-containing complex. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 5. Orthologous to human SPTAN1 (spectrin alpha, non-erythrocytic 1). [provided by Alliance of Genome Resources, Apr 2022]

Sptan1 Products(1)

mRNA Protein Name
NM_171983.3 NP_741984.3 spectrin alpha chain, non-erythrocytic 1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
11274145 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
15331416 RGD
enables spectrin binding IDA
IDA: Inferred from direct assay
23704327 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
11454415 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
16870704 RGD
is active in postsynapse IDA
IDA: Inferred from direct assay
11454415 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
15331416 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

spectrin alpha chain, non-erythrocytic 1

a--fodrin

alpha II spectrin

alpha-fodrin

alpha-spectrin 2

brain alpha-spectrin

fodrin alpha chain

inhibitory protein factor

noerythroid alpha-spectrin 2

nonerythroid alpha-spectrin 2

spectrin alpha chain, brain

spectrin, non-erythroid alpha chai

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13730 SPTAN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sptan1 NCBI NCBI:6709