2. Gene
  3. Pmpcb - peptidase, mitochondrial processing subunit beta Gene

Pmpcb - peptidase, mitochondrial processing subunit beta Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Mppb

Gene ID: 64198 | Gene type: protein coding

About Pmpcb

Summary

Enables metalloendopeptidase activity. Contributes to metallopeptidase activity. Involved in protein processing involved in protein targeting to mitochondrion. Located in mitochondrion. Part of mitochondrial processing peptidase complex. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome 6. Orthologous to human PMPCB (peptidase, mitochondrial processing subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Pmpcb Products(1)

mRNA Protein Name
NM_022395.2 NP_071790.1 mitochondrial-processing peptidase subunit beta precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables endopeptidase activity IDA
IDA: Inferred from direct assay
11563836 RGD
enables metalloendopeptidase activity IDA
IDA: Inferred from direct assay
10942759 RGD
contributes to metallopeptidase activity IDA
IDA: Inferred from direct assay
7490252 RGD
Biological Process GO Annotation Evidence Reference Source
involved in protein processing IDA
IDA: Inferred from direct assay
10942759 RGD
involved in protein processing involved in protein targeting to mitochondrion IDA
IDA: Inferred from direct assay
12433926 RGD
Cellular Component GO Annotation Evidence Reference Source
part of mitochondrial processing peptidase complex IDA
IDA: Inferred from direct assay
10942759 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitochondrial-processing peptidase subunit beta

P-52

beta-MPP

mitochondrial processing peptidase beta subunit

peptidase (mitochondrial processing) beta

peptidase, mitochondrial processing beta subunit

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10771 PMPCB Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pmpcb NCBI NCBI:9512