Smn1 - survival of motor neuron 1, telomeric Gene

Also Known as Smn

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 64301

Summary

Enables Fibroblast Growth Factor binding activity. Involved in chemical synaptic transmission. Located in Gemini of coiled bodies; cytoplasm; and nucleolus. Human ortholog(s) of this gene implicated in Werdnig-Hoffmann disease; adult spinal muscular atrophy; intermediate spinal muscular atrophy; juvenile spinal muscular atrophy; and spinal muscular atrophy. Orthologous to several human genes including SMN2 (survival of motor neuron 2, centromeric). [provided by Alliance of Genome Resources, Apr 2022]

Smn1 Products (1)

mRNA Protein Name
NM_022509.2 NP_071954.2 survival motor neuron protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables fibroblast growth factor binding IPI
IPI: Inferred from physical interaction
12397076 RGD
Biological Process GO Annotation Evidence References Source
involved in chemical synaptic transmission IEP
IEP: Inferred from expression pattern
12030329 RGD
Cellular Component GO Annotation Evidence References Source
located in Gemini of coiled bodies IDA
IDA: Inferred from direct assay
12397076 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

survival motor neuron protein

  • survival motor neuron 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-124266 ML104 / Unkown
HY-RS13438 SMN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22328 Smn1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Smn1 NCBI NCBI:6606